DP077-05 VEGFR-1 / Flt-1 antibody

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Regular Price: 0.5 ml / €350.00

Special Price: 0.5 ml / €245.00

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Quick Overview

Rabbit anti Human, Mouse, Rat VEGFR-1 / Flt-1

Product Description for VEGFR-1 / Flt-1

Rabbit anti Human, Mouse, Rat VEGFR-1 / Flt-1.
Presentation: Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for VEGFR-1 / Flt-1

Product Category Antibodies
Quantity 0.5 ml
Synonyms FLT, FLT1, FRT, Fms-like tyrosine kinase 1, FocusOn005, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, VEGF Receptor 1, VEGFR1, Vascular endothelial growth factor receptor 1, Vascular permeability factor receptor
Presentation Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
P17948
Immunogen:
A synthetic peptide derived from the C-terminus of the Flt-1 precursor of human origin
Genename:
2321
Antibody type Ab
Application Immunohistochemistry on Formalin-Fixed Paraffin Embedded Tissues: Use a dilution of 1/50-1/100 in an ABC method (incubation period of 30 minutes at room temperature).
Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0, prior to immunostaining.
Recommended Positive Control: Angiosarcoma.
Also useful for Western blotting.
Background VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes.
Flt-1 is a cell membrane receptor kinase. Flk-1 has a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis.
General Readings
  • Ahmed et al. Growth Factors 12: 235, 1995.
  • Ankam-Sey et al. Oncogene 17: 115, 1998.
  • Shibuya et al. Oncogene 5: 519, 1990.
Storage Store the antibody undiluted at 2-8°C.
Shelf life: One year from despatch.
Format
State:
Liquid purified Ig fraction with Sodium Azide as preservative.
Purified
Specificity
Specificity:
This antibody reacts with a 180 kD protein, known as Flt-1/Vascular Endothelial Growth Factor Receptor 1.
Cellular localization: cytoplasmic.
Species:
Human, Mouse and Rat.
Gene ID 2321
FocusOn and Reviews
FocusOns:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for VEGFR-1 / Flt-1 (14 products)

Catalog No. Species Pres. Purity   Source  
AR00181PU-N

VEGFR-1 / Flt-1 (His-tagged), Active Enzyme

VEGFR-1 / Flt-1 Human Purified > 70 % SF9 cells
10 µg / €300.00
  Acris Antibodies GmbH
DA3532

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human Purified > 85 % Insect cells
5 µg / €160.00
  Acris Antibodies GmbH
DA3532X

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human Purified > 85 % Insect cells
20 µg / €240.00
  Acris Antibodies GmbH
DA3533

VEGFR-1 / Flt-1 (D1-D4)

VEGFR-1 / Flt-1 Human Purified > 60 % Insect cells
5 µg / €170.00
  Acris Antibodies GmbH
DA3533X

VEGFR-1 / Flt-1 (D1-D4)

VEGFR-1 / Flt-1 Human Purified > 60 % Insect cells
20 µg / €280.00
  Acris Antibodies GmbH
DA3534

VEGFR-1 / Flt-1 (Fc Chimera)

VEGFR-1 / Flt-1 Human Purified > 95 % Insect cells
10 µg / €150.00
  Acris Antibodies GmbH
DA3534X

VEGFR-1 / Flt-1 (Fc Chimera)

VEGFR-1 / Flt-1 Human Purified > 95 % Insect cells
50 µg / €270.00
  Acris Antibodies GmbH
DA3539

VEGFR-1 / Flt-1 (D1-D5)

VEGFR-1 / Flt-1 Human Purified > 90 % Insect cells
5 µg / €160.00
  Acris Antibodies GmbH
DA3539X

VEGFR-1 / Flt-1 (D1-D5)

VEGFR-1 / Flt-1 Human Purified > 90 % Insect cells
20 µg / €240.00
  Acris Antibodies GmbH
DA3541

VEGFR-1 / Flt-1 (D1-D3)

VEGFR-1 / Flt-1 Human Purified > 90 % Insect cells
5 µg / €170.00
  Acris Antibodies GmbH
DA3541X

VEGFR-1 / Flt-1 (D1-D3)

VEGFR-1 / Flt-1 Human Purified > 90 % Insect cells
20 µg / €280.00
  Acris Antibodies GmbH
NBP1-94701

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human Purified
10 µg / €390.00
  Novus Biologicals Inc.
H00002321-Q01-10

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00002321-Q01-25

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for VEGFR-1 / Flt-1 (2 products)

Catalog No. Species Pres. Purity   Source  
H00002321-T01

FLT1 293T Cell Transient Overexpression Lysate(Denatured)

FLT1 293T Cell Transient Overexpression Lysate(Denatured)
0.1 ml / €240.00
  Abnova Taiwan Corp.
NBL1-06699

VEGF Receptor 1 Lysate

Western Blot: VEGFR1 Antibody [NB100-527] - Western Blot on VEGFR1 (A) empty vector control and (B) overexpression lysates [NBL1-06699].
0.1 ml / €170.00
  Novus Biologicals Inc.