DP3522 VEGFR-1 / Flt-1 (C-term) antibody

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0.2 mg / €340.00
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Rabbit anti Human VEGFR-1 / Flt-1

DP3522

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  • DP3522

Product Description for VEGFR-1 / Flt-1

Rabbit anti Human VEGFR-1 / Flt-1.
Properties: (C-term)
Presentation: Azide Free
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for VEGFR-1 / Flt-1

Product Category Antibodies
Quantity 0.2 mg
Synonyms FLT, FLT1, FRT, Fms-like tyrosine kinase 1, FocusOn005, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, VEGF Receptor 1, VEGFR1, Vascular endothelial growth factor receptor 1, Vascular permeability factor receptor
Presentation Azide Free
Reactivity Hu
Applications ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
P17948
Immunogen:
Peptide of the C-terminal end of native Human soluble VEGFR-1/Flt-1
AA Sequence:
CNKKAVFSRISKFKSTRNDSTTQSNVKH
Genename:
2321
Property C-term
Antibody type Ab
Application Western Blot: This VEGFR1 antibody can be used at 0.5-2.0 µg/ml with the appropriate secondary reagents to detect native Human sVEGFR-1/Flt-1.
Immunofluorescence.
Background Three cell membrane receptor tyrosine kinases, Flt (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulinlike sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors, including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.
Storage Prior to reconstitution store at 2-8°C for one month or at -20°C for longer.
Following reconstitution store the antibody undiluted at 2-8°C for one month.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein A Chromatography.
Buffer System:
PBS, pH 7.2 without preservatives or stabilizers.
State:
Lyophilized purified Ig fraction.
Azide Free
Reconstitution:
Restore in sterile water to a concentration of > 0.5 mg/ml
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody recognizes the recombinant soluble VEGFR-1/FLT-1 (native) but not the recombinant soluble VEGFR-1/FLT-1 (D1-5) both produced in Insects cells. Because of the different glycosylation of insect cells compared to mammalian cells the MW of sFlt-1 (native) is about 96 kDa instead of about 110 kDa of the naturally occurring sFlt-1.
The antibody did not cross react with recombinant Human soluble KDR (D1-7).
Gene ID 2321
FocusOn and Reviews
FocusOns:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for VEGFR-1 / Flt-1 (14 products)

Catalog No. Species Pres. Purity   Source  
AR00181PU-N

VEGFR-1 / Flt-1 (His-tagged), Active Enzyme

VEGFR-1 / Flt-1 Human Purified > 70 % SF9 cells
10 µg / €300.00
  Acris Antibodies GmbH
DA3532

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human Purified > 85 % Insect cells
5 µg / €160.00
  Acris Antibodies GmbH
DA3532X

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human Purified > 85 % Insect cells
20 µg / €240.00
  Acris Antibodies GmbH
DA3533

VEGFR-1 / Flt-1 (D1-D4)

VEGFR-1 / Flt-1 Human Purified > 60 % Insect cells
5 µg / €170.00
  Acris Antibodies GmbH
DA3533X

VEGFR-1 / Flt-1 (D1-D4)

VEGFR-1 / Flt-1 Human Purified > 60 % Insect cells
20 µg / €280.00
  Acris Antibodies GmbH
DA3534

VEGFR-1 / Flt-1 (Fc Chimera)

VEGFR-1 / Flt-1 Human Purified > 95 % Insect cells
10 µg / €150.00
  Acris Antibodies GmbH
DA3534X

VEGFR-1 / Flt-1 (Fc Chimera)

VEGFR-1 / Flt-1 Human Purified > 95 % Insect cells
50 µg / €270.00
  Acris Antibodies GmbH
DA3539

VEGFR-1 / Flt-1 (D1-D5)

VEGFR-1 / Flt-1 Human Purified > 90 % Insect cells
5 µg / €160.00
  Acris Antibodies GmbH
DA3539X

VEGFR-1 / Flt-1 (D1-D5)

VEGFR-1 / Flt-1 Human Purified > 90 % Insect cells
20 µg / €240.00
  Acris Antibodies GmbH
DA3541

VEGFR-1 / Flt-1 (D1-D3)

VEGFR-1 / Flt-1 Human Purified > 90 % Insect cells
5 µg / €170.00
  Acris Antibodies GmbH
DA3541X

VEGFR-1 / Flt-1 (D1-D3)

VEGFR-1 / Flt-1 Human Purified > 90 % Insect cells
20 µg / €280.00
  Acris Antibodies GmbH
NBP1-94701

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human Purified
10 µg / €390.00
  Novus Biologicals Inc.
H00002321-Q01-10

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00002321-Q01-25

VEGFR-1 / Flt-1

VEGFR-1 / Flt-1 Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for VEGFR-1 / Flt-1 (2 products)

Catalog No. Species Pres. Purity   Source  
H00002321-T01

FLT1 293T Cell Transient Overexpression Lysate(Denatured)

FLT1 293T Cell Transient Overexpression Lysate(Denatured)
0.1 ml / €240.00
  Abnova Taiwan Corp.
NBL1-06699

VEGF Receptor 1 Lysate

Western Blot: VEGFR1 Antibody [NB100-527] - Western Blot on VEGFR1 (A) empty vector control and (B) overexpression lysates [NBL1-06699].
0.1 ml / €170.00
  Novus Biologicals Inc.