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Antibodies and related products for scientific research: primary antibodies: 109,081, secondary ab: 1,960, proteins: 34,638, kits: 272, lysates: 2,997, RNAi: 30,480, tissue slides: 2,211, other products: 1,480

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Antibodies to 5-hydroxytryptamine (Serotonin) Receptors

Introduction: 5-hydroxytryptamine (5-HT), also known as Serotonin, is probably unique among the monoamines in that its effects are subserved by as many as thirteen distinct heptahelical, G-protein-coupled receptors (GPCRs) and one (presumably a family of) ligand-gated ion channel(s). These receptors are divided into seven distinct classes [5-HT(1) to 5-HT(7)] largely on the basis of their structural and operational characteristics.

Whilst this degree of physical diversity clearly underscores the physiological importance of serotonin, evidence for an even greater degree of operational diversity continues to emerge. The challenge for modern 5-HT research has therefore been to define more precisely the properties of the systems that make this incredible diversity possible. Much progress in this regard has been made during the last decade with the realisation that serotonin is possibly the least conservative monoamine transmitter and the cloning of its many receptors. Coupled with the actions of an extremely avid and efficient reuptake system, this array of receptor subtypes provides almost limitless signalling capabilities to the extent that one might even question the need for other transmitter systems. However, the complexity of the system appears endless, since posttranslational modifications, such as alternate splicing and RNA editing, increase the number of proteins, oligomerisation and heteromerisation increase the number of complexes, and multiple G-protein suggest receptor trafficking, allowing phenotypic switching and crosstalk within and possibly between receptor families. Whether all these possibilities are used in vivo under physiological or pathological conditions remains to be firmly established.

Antibody Tools for the Specific Detection of 5-HT Receptors

For specific detection of the 13 serotonin receptor subtypes a unique antibody panel is available from Acris Antibodies. All antibodies were made using receptor specific peptides for immunisation. Every single antibody was tested thoroughly for the applications listed in the table below. A picture gallery at the end of this article shows staining results achieved using these products.



Vascular smooth muscle paraffin section stained with SP4041P for 5-HT1BR

Vascular smooth muscle paraffin section stained with SP4041P for 5-HT1BR

Human Kidney renal tubules paraffin section stained with SP4045P for 5-HT1FR

Human Kidney renal tubules paraffin section stained with SP4045P for 5-HT1FR

Rat brain frozen section stained with 24288 for 5-HT2AR

Rat brain frozen section stained with 24288 for 5-HT2AR

Human heart paraffin section stained with SP4046P for 5-HT2BR

Human heart paraffin section stained with SP4046P for 5-HT2BR

Human kidney renal tubules paraffin section stained with SP4047P for 5-HT2BR

Human kidney renal tubules paraffin section stained with SP4047P for 5-HT2BR

Human brain vessel paraffin section stained with SP4048P for 5-HT4R

Human brain vessel paraffin section stained with SP4048P for 5-HT4R

Human brain neurons paraffin section stained with SP4049P for 5-HT6R

Human brain neurons paraffin section stained with SP4049P for 5-HT6R

Small intestine smooth muscle section stained SP4050P for 5-HT7R

Small intestine smooth muscle section stained SP4050P for 5-HT7R

Small intestine paraffin section stained with SP4051P for 5-HT7R

Small intestine paraffin section stained with SP4051P for 5-HT7R

Staining of 5-HT1B Receptor antibody SP7000P, 5-HT1D Receptor antibody SP7001P, 5-HT3 Receptor antibody SP7002P, and 5-HT7 Receptor antibody SP7003P (from left to right) using human brain cell lysates at 1-2 µg/ml dilution.

Staining of 5-HT1B Receptor antibody SP7000P, 5-HT1D Receptor antibody SP7001P, 5-HT3 Receptor antibody SP7002P, and 5-HT7 Receptor antibody SP7003P (from left to right) using human brain cell lysates at 1-2 µg/ml dilution.

Rabbit anti 5-HT3B antibody ARP35186 staining of paraffin embedded human spleen: cells with positive label are indicated with arrows Rabbit anti 5-HT3B antibody ARP35186 staining of paraffin embedded human spleen: cells with positive label are indicated with arrows

Antibody Panel to Serotonin Receptors

Serotonin receptor (5-hydroxytryptamine receptor / 5-HT) : HTR1A (5-HT1A Receptor, 5-HT1AR), HTR1B, HTR1D, HTR1E, HTR1F, HTR2A, HTR2B, HTR2C, HTR3A, HTR3B, HTR4, HTR5A, HTR6, HTR7, and HTRA2



Found 109 items

Antibodies


Catalog No. Host Clone/Iso. Presentation   Reactivity Applications  
20081 5-HT (Serotonin) / BSA Conjugate Control Control Peptide 
  Purified 0.05 mg / 180 €
    ImmunoStar Inc.
 
AP06769PU-N 5-HT1A / HTR1A antibody 
 Rabbit Aff - Purified Hu, Ms, Rt E, WB 100 µg / 330 €
    Acris Antibodies GmbH
 
24504 5-HT1A / HTR1A antibody 
 Rabbit Serum Hu, Ms, Rt C, WB 0.1 ml / 410 €
    ImmunoStar Inc.
 
RA24504-100 5-HT1A / HTR1A antibody 
 Rabbit Serum Hu, Ms, Rt C, WB 0.1 ml / 450 €
    Neuromics Antibodies
 
NB100-1890 5-HT1A / HTR1A antibody 
 Goat Aff - Purified Hu, Ms, Rt E, WB 0.1 mg / 260 €
  IgG   Novus Biologicals Inc.
 
AVARP13041_P050 5-HT1A / HTR1A antibody 
 Rabbit Aff - Purified Hu WB 50 µg / 330 €
  IgG   AVIVA Systems Biology
 
AVARP13041_T100 5-HT1A / HTR1A antibody 
 Rabbit Purified Hu WB 0.1 mg / 290 €
  IgG   AVIVA Systems Biology
 
EB06787 5-HT1A / HTR1A antibody 
 Goat Aff - Purified Hu, Ms, Rt, Can 0.1 mg / 210 €
    Everest Biotech Ltd.
 
SP4041P 5-HT1B (HTR1B) antibody 
 Rabbit Aff - Purified Hu, Ms, Rt P 50 µg / 380 €
    Acris Antibodies GmbH
 
AP16493PU-N 5-HT1B / HTR1B antibody 
 Goat Aff - Purified Hu, Ms, Rt, Can WB 0.1 mg / 250 €
    Acris Antibodies GmbH
 
SP7000P 5-HT1B / HTR1B antibody 
 Rabbit Purified Hu, Ms, Rt WB 0.1 mg / 280 €
    Acris Antibodies GmbH
 
NB100-41091 5-HT1B / HTR1B antibody 
 Goat Aff - Purified Hu E, WB 0.1 mg / 360 €
  IgG   Novus Biologicals Inc.
 
NB100-41091PEP 5-HT1B / HTR1B Control Peptide 
  0.1 mg / 210 €
    Novus Biologicals Inc.
 
NB100-56350 5-HT1B / HTR1B antibody 
 Rabbit 5-GT1B Aff - Purified Hu, Ms, Rt WB 0.1 mg / 360 €
  IgG   Novus Biologicals Inc.
 
NLS598 5-HT1B / HTR1B antibody 
 Rabbit Aff - Purified Hu P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
AVARP13042_T100 5-HT1B / HTR1B antibody 
 Rabbit Purified Hu WB 0.1 mg / 290 €
  IgG   AVIVA Systems Biology
 
EB07259 5-HT1B / HTR1B antibody 
 Goat Aff - Purified Hu, Ms, Rt, Can WB 0.1 mg / 310 €
    Everest Biotech Ltd.
 
SP4688P 5-HT1D / HTR1D (3rd. cytopl. Dom.) antibody 
 Rabbit Aff - Purified Hu, Ms, Rt P 50 µg / 330 €
    Acris Antibodies GmbH
 
SP4689P 5-HT1D / HTR1D (N-term. extracell. Dom.) antibody 
 Rabbit Aff - Purified Hu P 50 µg / 330 €
    Acris Antibodies GmbH
 
SP4690P 5-HT1D / HTR1D (3rd. cytopl. Dom.) antibody 
 Rabbit Aff - Purified Hu, Ms, Rt P 50 µg / 330 €
    Acris Antibodies GmbH
 
SP4691P 5-HT1D / HTR1D (2nd. extracell. Dom.) antibody 
 Rabbit Aff - Purified Hu, Ms, Rt P 50 µg / 330 €
    Acris Antibodies GmbH
 
SP7001P 5-HT1D / HTR1D antibody 
 Rabbit Purified Hu, Ms, Rt WB 0.1 mg / 280 €
    Acris Antibodies GmbH
 
NB100-56349 5-HT1D / HTR1D antibody 
 Rabbit 5-HT1DR Aff - Purified Hu, Ms, Rt WB 0.1 mg / 360 €
  IgG   Novus Biologicals Inc.
 
NLS577 5-HT1D / HTR1D antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
NLS588 5-HT1D / HTR1D antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
NLS589 5-HT1D / HTR1D antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
NLS590 5-HT1D / HTR1D antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
AP06986PU-N 5-HT1E / HTR1E antibody 
 Rabbit Aff - Purified Hu P 50 µg / 380 €
    Acris Antibodies GmbH
 
RA30000-50 5-HT1E / HTR1E (3rd Cytopl. Dom) antibody 
 Rabbit Aff - Purified Hu, Rt C, P 50 µg / 460 €
  IgG   Neuromics Antibodies
 
NLS2739 5-HT1E / HTR1E antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
AP07067PU-N 5-HT1F / HTR1F antibody 
 Rabbit Aff - Purified Hu P 50 µg / 360 €
    Acris Antibodies GmbH
 
SP4043P 5-HT1F / HTR1F (extracell. Dom.) antibody 
 Rabbit Aff - Purified Hu, Ms, Rt P 50 µg / 330 €
    Acris Antibodies GmbH
 
SP4044P 5-HT1F / HTR1F (cytoplasm. Dom.) antibody 
 Rabbit Aff - Purified Hu, Ms, Rt P 50 µg / 330 €
    Acris Antibodies GmbH
 
SP4045P 5-HT1F / HTR1F (cytoplasm. Dom.) antibody 
 Rabbit Aff - Purified Hu, Ms, Rt P 50 µg / 330 €
    Acris Antibodies GmbH
 
RA30002-50 5-HT1F / HTR1F (3rd Cytopl. Dom.) antibody 
 Rabbit Aff - Purified Hu C, P 50 µg / 460 €
  IgG   Neuromics Antibodies
 
NLS3338 5-HT1F / HTR1F antibody 
 Rabbit Aff - Purified Hu P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
NLS3343 5-HT1F / HTR1F antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
NLS3344 5-HT1F / HTR1F antibody 
 Rabbit Aff - Purified Hu P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
AVARP13073_T100 5-HT1F / HTR1F antibody 
 Rabbit Purified Hu WB 0.1 mg / 290 €
  IgG   AVIVA Systems Biology
 
24288 5-HT2A / HTR2A antibody 
 Rabbit Serum Ms, Rt C, IF, WB 0.1 ml / 410 €
    ImmunoStar Inc.
 
24333 5-HT2A / HTR2A Control Peptide 
  Purified 25 µg / 130 €
    ImmunoStar Inc.
 
RA24288-100 5-HT2A / HTR2A antibody 
 Rabbit Serum Ms, Rt C, IF, WB 0.1 ml / 450 €
    Neuromics Antibodies
 
EB08522 5-HT2A / HTR2A antibody 
 Goat Aff - Purified Hu 0.1 mg / 210 €
    Everest Biotech Ltd.
 
SP4046P 5-HT2B / HTR2B (2nd extracell. Dom) antibody 
 Rabbit Aff - Purified Hu, Ms, Rt P 50 µg / 380 €
    Acris Antibodies GmbH
 
SP4047P 5-HT2B / HTR2B (N-term) antibody 
 Rabbit Aff - Purified Hu P 50 µg / 380 €
    Acris Antibodies GmbH
 
NLS1111 5-HT2B / HTR2B antibody 
 Rabbit Aff - Purified Hu P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
NLS1187 5-HT2B / HTR2B antibody 
 Rabbit Aff - Purified Hu P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
GB-30110 5-HT2B / HTR2B (Extracell. Dom) antibody 
 Rabbit Aff - Purified Hu 0.1 ml / 290 €
    Genesis Biotech Inc.
 
AP00330PU-N 5-HT2C / HTR2C antibody 
 Rabbit Aff - Purified Hu WB 0.1 mg / 290 €
    Acris Antibodies GmbH
 
AP16378PU-N 5-HT2C / HTR2C (internal) antibody 
 Goat Aff - Purified Hu, Ms, Rt, Can WB 0.1 mg / 250 €
    Acris Antibodies GmbH
 
SP4624P 5-HT2C / HTR2C (cytopl. Dom.) antibody 
 Rabbit Aff - Purified Hu P 50 µg / 330 €
    Acris Antibodies GmbH
 
SP4625P 5-HT2C / HTR2C (cytopl. Dom.) antibody 
 Rabbit Aff - Purified Hu P 50 µg / 330 €
    Acris Antibodies GmbH
 
SP4626P 5-HT2C / HTR2C antibody 
 Rabbit Aff - Purified Hu P 50 µg / 330 €
    Acris Antibodies GmbH
 
24505 5-HT2C / HTR2C antibody 
 Rabbit Serum Hu, Ms, Rt C, WB 0.1 ml / 410 €
    ImmunoStar Inc.
 
RA24505-100 5-HT2C / HTR2C antibody 
 Rabbit Serum Hu, Ms, Rt C, WB 0.1 ml / 450 €
    Neuromics Antibodies
 
NB100-1524 5-HT2C / HTR2C antibody 
 Goat Aff - Purified Hu, Ms, Rt E, WB 0.1 mg / 360 €
  IgG   Novus Biologicals Inc.
 
NLS1115 5-HT2C / HTR2C antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
NLS1116 5-HT2C / HTR2C antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
NLS1119 5-HT2C / HTR2C antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
AVARP13045_T100 5-HT2C / HTR2C antibody 
 Rabbit Purified Hu WB 0.1 mg / 290 €
  IgG   AVIVA Systems Biology
 
EB06786 5-HT2C / HTR2C (internal) antibody 
 Goat Aff - Purified Hu, Ms, Rt, Can WB 0.1 mg / 310 €
    Everest Biotech Ltd.
 
SP7002P 5-HT3 / HTR3 antibody 
 Rabbit Purified Hu, Rt WB 0.1 mg / 280 €
    Acris Antibodies GmbH
 
NB100-56351 5-HT3 / HTR3 antibody 
 Rabbit 5-HT3 Aff - Purified Hu, Rt WB 0.1 mg / 360 €
  IgG   Novus Biologicals Inc.
 
AP16518PU-N 5-HT3A / HTR3A antibody 
 Goat Aff - Purified Hu WB 0.1 mg / 250 €
    Acris Antibodies GmbH
 
NB100-41382 5-HT3A / HTR3A antibody 
 Goat Aff - Purified Hu E, WB 0.1 mg / 360 €
  IgG   Novus Biologicals Inc.
 
NB100-41382PEP 5-HT3A / HTR3A Control Peptide 
  0.1 mg / 210 €
    Novus Biologicals Inc.
 
10443-1-AP 5-HT3A / HTR3A antibody 
 Rabbit Aff - Purified Hu, Ms E, WB 150 µl / 280 €
  IgG   ProteinTech Group, Inc.
 
AVARP13046_P050 5-HT3A / HTR3A antibody 
 Rabbit Aff - Purified Hu P, WB 50 µg / 330 €
  IgG   AVIVA Systems Biology
 
AVARP13046_T100 5-HT3A / HTR3A antibody 
 Rabbit Purified Hu WB 0.1 mg / 290 €
  IgG   AVIVA Systems Biology
 
EB07328 5-HT3A / HTR3A antibody 
 Goat Aff - Purified Hu WB 0.1 mg / 310 €
    Everest Biotech Ltd.
 
ARP35186_P050 5-HT3B / HTR3B antibody 
 Rabbit Aff - Purified Hu P, WB 50 µg / 330 €
    AVIVA Systems Biology
 
SP4048P 5-HT4 / HTR4 antibody 
 Rabbit Aff - Purified Hu, Ms, Rt P 50 µg / 380 €
    Acris Antibodies GmbH
 
NLS655 5-HT4 / HTR4 antibody 
 Rabbit Aff - Purified Hu P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
NLS656 5-HT4 / HTR4 antibody 
 Rabbit Aff - Purified Hu, Rt C 0.05 ml / 440 €
    Novus Biologicals Inc.
 
AP01011PU-N 5-HT5A / HTR5A (1st. Extracell. Dom.) antibody 
 Rabbit Aff - Purified Hu, Rt P 50 µg / 380 €
    Acris Antibodies GmbH
 
AP06848PU-N 5-HT5A / HTR5A (N-term) antibody 
 Rabbit Aff - Purified Hu P 50 µg / 380 €
    Acris Antibodies GmbH
 
AP06849PU-N 5-HT5A / HTR5A (1st. Extracell. Dom.) antibody 
 Rabbit Aff - Purified Hu, Ms, Rt P 50 µg / 360 €
    Acris Antibodies GmbH
 
AP06995PU-N 5-HT5A / HTR5A antibody 
 Rabbit Aff - Purified Hu P 50 µg / 360 €
    Acris Antibodies GmbH
 
SP4652P 5-HT5A / HTR5A (3rd. Cytopl. Dom.) antibody 
 Rabbit Aff - Purified Hu P 50 µg / 330 €
    Acris Antibodies GmbH
 
SP4653P 5-HT5A / HTR5A (3rd. cytopl. Dom.) antibody 
 Rabbit Aff - Purified Hu, Ms, Rt P 50 µg / 330 €
    Acris Antibodies GmbH
 
24429 5-HT5A / HTR5A antibody 
 Rabbit Serum Ms, Rt C, IF, WB 0.1 ml / 410 €
    ImmunoStar Inc.
 
RA24429-100 5-HT5A / HTR5A antibody 
 Rabbit Serum Ms, Rt C, IF, WB 0.1 ml / 450 €
    Neuromics Antibodies
 
RA30001-50 5-HT5A / HTR5A (3rd Cytopl. Dom.) antibody 
 Rabbit Aff - Purified Hu, Rt C, P 50 µg / 460 €
  IgG   Neuromics Antibodies
 
NB100-58982 5-HT5A / HTR5A antibody 
 Rabbit Aff - Purified Hu P 0.05 mg / 420 €
  IgG   Novus Biologicals Inc.
 
NB100-58983 5-HT5A / HTR5A antibody 
 Rabbit Aff - Purified Hu P 0.05 mg / 420 €
  IgG   Novus Biologicals Inc.
 
NB100-59010 5-HT5A / HTR5A antibody 
 Rabbit Aff - Purified Hu P 0.05 mg / 420 €
  IgG   Novus Biologicals Inc.
 
NLS2121 5-HT5A / HTR5A antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
NLS2122 5-HT5A / HTR5A antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
SP4049P 5-HT6 / HTR6 (C-term) antibody 
 Rabbit Aff - Purified Hu, Ms, Rt P 50 µg / 380 €
    Acris Antibodies GmbH
 
NLS650 5-HT6 / HTR6 antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
NLS652 5-HT6 / HTR6 antibody 
 Rabbit Aff - Purified Hu C 0.05 ml / 440 €
    Novus Biologicals Inc.
 
SP4050P 5-HT7 / HTR7 (C-term) antibody 
 Rabbit Aff - Purified Hu P 50 µg / 380 €
    Acris Antibodies GmbH
 
SP4051P 5-HT7 / HTR7 antibody 
 Rabbit Aff - Purified Hu P 50 µg / 380 €
    Acris Antibodies GmbH
 
SP7003P 5-HT7 / HTR7 antibody 
 Rabbit Purified Hu, Ms, Rt, Can WB 0.1 mg / 280 €
    Acris Antibodies GmbH
 
24430 5-HT7 / HTR7 antibody 
 Rabbit Serum Hu, Ms, Rt C, WB 0.1 ml / 410 €
    ImmunoStar Inc.
 
RA24430-100 5-HT7 / HTR7 antibody 
 Rabbit Serum Hu, Ms, Rt C, WB 0.1 ml / 450 €
    Neuromics Antibodies
 
NB100-56352 5-HT7 / HTR7 antibody 
 Rabbit Purified Hu, Ms, Rt, Can WB 0.1 mg / 360 €
  IgG   Novus Biologicals Inc.
 
NB100-59008 5-HT7 / HTR7 antibody 
 Rabbit Aff - Purified Hu P 0.05 mg / 390 €
  IgG   Novus Biologicals Inc.
 
NB100-59009 5-HT7 / HTR7 antibody 
 Rabbit Aff - Purified Hu P 0.05 mg / 420 €
  IgG   Novus Biologicals Inc.
 
NB100-59016 5-HT7 / HTR7 antibody 
 Rabbit Aff - Purified Hu P 0.05 mg / 390 €
  IgG   Novus Biologicals Inc.
 
NLS663 5-HT7 / HTR7 antibody 
 Rabbit Aff - Purified Hu P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
NLS6674 5-HT7 / HTR7 antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
NLS6675 5-HT7 / HTR7 antibody 
 Rabbit Aff - Purified Hu C, P 0.05 ml / 440 €
    Novus Biologicals Inc.
 
AVARP13048_P050 5-HT7 / HTR7 (adenylate cyclase-coupled)) antibody 
 Rabbit Aff - Purified Hu WB 50 µg / 330 €
  IgG   AVIVA Systems Biology
 
AVARP13048_T100 5-HT7 / HTR7 (adenylate cyclase-coupled)) antibody 
 Rabbit Purified Hu WB 0.1 mg / 290 €
  IgG   AVIVA Systems Biology
 
AP06987PU-N 5-HT7 Receptor (HTR7) (3rd. Cytopl. Dom) antibody 
 Rabbit Aff - Purified Hu P 50 µg / 380 €
    Acris Antibodies GmbH
 
AP06994PU-N 5-HT7 Receptor (HTR7) (N-term) antibody 
 Rabbit Aff - Purified Hu P 50 µg / 380 €
    Acris Antibodies GmbH
 
AP07036PU-N 5-HT7 Receptor (HTR7) (C-term) antibody 
 Rabbit Aff - Purified Hu, Ms P 50 µg / 380 €
    Acris Antibodies GmbH
 
AP01244PU-N Serotonin Receptor 5A (SR-5A) antibody 
 Rabbit Aff - Purified Hu WB 100 µg / 330 €
    Acris Antibodies GmbH