Antibody panel to Epithelial Cell Adhesion Molecule (EpCAM)

Introduction

Epithelial Cell Adhesion Molecule (EpCAM) is a 40kD cell surface antigen. This antigen has been identified independently by a number of groups, and has been known by a variety of names (CD326, KSA, ESA, Lymphocyte antigen 74, M1S2, M4S1, GA733 2, MIC18, MK1, TACSTD1, TROP1).

Several monoclonal antibodies have been raised against EpCAM, many of which have been described as tumour specific molecules on carcinomas. EpCAM is a Type 1 transmembrane glycoprotein. It is expressed on the basolateral membrane of cells by the majority of epithelial tissues, with the exception of adult squamous epithelium and some specific epithelial cell types including hepatocytes and gastric epithelial cells. EpCAM expression has been reported to be a possible marker of early malignancy, with expression being increased in tumour cells, and de novo expression being seen in dysplastic squamous epithelium.

Antibody Panel to Epithelia Cell Adhesion Molecule (Ep-Cam)

Acris Antibodies offers a full range of monoclonal antibodies for specific detetction of EpCAM in human and rat tissues using western blotting or immunohistochemistry. For staining pictures see gallery below.

Antibody Panel to EpCAM (Ep-CAM antibody, CD326 antibody, KSA antibody, ESA antibody, Lymphocyte antigen 74 antibody, M1S2 antibody, M4S1 antibody, GA733 2 antibody, MIC18 antibody, MK1 antibody, TACSTD1 antibody, TROP1 antibody)

Known synonyms: CD326, KSA, ESA, Lymphocyte antigen 74, M1S2, M4S1, GA733 2, MIC18, MK1, TACSTD1, TROP1