Antibodies to Androgen Receptor - FocusOn 052

Introduction

Androgens are steroid hormones that are necessary for normal male phenotype expression, including the outward development of secondary sex characteristics as well as the initiation and maintenance of spermatogenesis.

Many physiological actions of androgens are mediated by the androgen receptor (AR). AR functions as a ligand-dependent transcription factor, regulating expression of an array of target genes that are important in male pubertal development and fertility.

The androgen receptor plays a pivotal role in the prostate. Its primary function is to provide responsive gene products for differentiation and growth, but under abnormal conditions it contributes to the development of prostate cancer.

AR is a 110 kD protein and a member of the steroid/nuclear receptor gene superfamily. The PI3K/Akt pathway regulates AR activity by inducing its phosphorylation at Ser210 and Ser790.

Antibody Tools for the Detection of Androgen Receptor

Acris Antibodies offers a panel of monoclonal and polyclonal antibodies for the detection of androgen receptor in several species. Antibodies can be used for immunohistochemistry, western blotting and other immunologicals methods.

Staining of human prostate using DM245P. Note nuclear staining of glandular epithelial cellsStaining of primate brain sections using SM5020PWestern blot anaylsis of mouse brain lysate using SP5177P

Fig.1: Formalin-fixed, paraffin-embedded human prostate stained with Androgen Receptor antibody AM00244PU-N

Fig.2: Staining of primate brain section using Androgen Receptor antibody SM5020P

Fig.3: Western blot of human brain lysate using Androgen Receptor antibody EB06441

Available Antibody Panel to Androgen Receptor

Anti- Androgen Receptor (Dihydrotestosterone Receptor, DHTR, NR3C4)

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Antibodies

Catalog No. Host Clone/Iso. Pres. React. Applications  
AP15348PU-N

Androgen receptor antibody

Human prostate ca. stained with Anti-AR antibody Rabbit Purified Hu, Ms, Rt ICC/IF, IP, P, WB
1 ml / €410.00
    Acris Antibodies GmbH
 
AP15348PU-S

Androgen receptor antibody

Human prostate ca. stained with Anti-AR antibody Rabbit Purified Hu, Ms, Rt P, WB
0.1 ml / €180.00
    Acris Antibodies GmbH
 
AM00244PU-N

Androgen receptor antibody

Formalin-fixed, paraffin-embedded human prostate stained with Androgen Receptor Ab (Cat.AM00244PU-N) using peroxidase-conjugate and DAB chromogen. Note nuclear staining of glandular epithelial cells. Mouse AR441 Purified Can, Hu C, ICC/IF, IP, P, WB
0.1 mg / €460.00
  IgG1   Acris Antibodies GmbH
 
AP00529PU-N

Androgen receptor antibody

Formalin-fixed, paraffin-embedded human prostate stained with Androgen Receptor (AP00529PU-N) using peroxidase-conjugate and AEC chromogen. Note nuclear staining of glandular epithelium. Rabbit Purified Hu, Ms, Rt ICC/IF, IP, P, WB
0.5 mg / €460.00
    Acris Antibodies GmbH
 
AP01524PU-N

Androgen receptor pSer213 antibody

Immunohistochemistry (IHC) analysis of p-Androgen Receptor antibody (Cat.-No.: AP01524PU-N) in paraffin-embedded human prostate carcinoma tissues Rabbit Aff - Purified Hu P
0.1 mg / €320.00
    Acris Antibodies GmbH
 
AP01525PU-N

Androgen receptor pSer650 antibody

Immunohistochemistry (IHC) analysis of p-Androgen Receptor (pSer650) antibody (Cat.-No.: AP01525PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu P
0.1 mg / €320.00
    Acris Antibodies GmbH
 
AP05354PU-N

Androgen receptor antibody

Androgen receptor Rabbit Purified P
1 ml / €420.00
  IgG   Acris Antibodies GmbH
 
AP06010PU-N

Androgen receptor antibody

Immunohistochemical analysis using Androgen receptor antibody Cat.-No. AP06010PU-N in Paraffin-embedded human prostate carcinoma tissue. Rabbit Aff - Purified Hu E, P
0.1 mg / €320.00
    Acris Antibodies GmbH
 
AP06011PU-N

Androgen receptor antibody

Immunohistochemical analysis using Androgen receptor  antibody Cat.-No. AP06011PU-N in Paraffin-embedded human prostate carcinoma tissue. Rabbit Aff - Purified Hu E, P, WB
0.1 mg / €320.00
    Acris Antibodies GmbH
 
AP08008PU-N

Androgen receptor pSer213 antibody

Figure 1. Western blot analysis of extract from DU145 cell, using Androgen Receptor (phospho-Ser213) antibody (#AP08008PU). Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €320.00
    Acris Antibodies GmbH
 
AP08008PU-S

Androgen receptor pSer213 antibody

Figure 1. Western blot analysis of extract from DU145 cell, using Androgen Receptor (phospho-Ser213) antibody (#AP08008PU). Rabbit Aff - Purified Hu ICC/IF, WB
50 µg / €240.00
    Acris Antibodies GmbH
 
AP08009PU-N

Androgen receptor pSer650 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Androgen Receptor pSer650 antibody (AP08009PU). Rabbit Aff - Purified Hu P
0.1 mg / €320.00
    Acris Antibodies GmbH
 
AP08009PU-S

Androgen receptor pSer650 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Androgen Receptor pSer650 antibody (AP08009PU). Rabbit Aff - Purified Hu P
50 µg / €240.00
    Acris Antibodies GmbH
 
AP09465PU-N

Androgen receptor antibody

Western blot analysis of extracts from Rat testis tissue using Androgen Receptor antibody AP09465PU Rabbit Aff - Purified Hu WB
0.1 mg / €270.00
    Acris Antibodies GmbH
 
AP09465PU-S

Androgen receptor antibody

Western blot analysis of extracts from Rat testis tissue using Androgen Receptor antibody AP09465PU Rabbit Aff - Purified Hu WB
50 µg / €230.00
    Acris Antibodies GmbH
 
AP16257PU-N

Androgen receptor (N-term) antibody

AP16257PU-N (0.3 µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €270.00
    Acris Antibodies GmbH
 
BM5059

Androgen receptor (N-term) antibody

Androgen receptor Mouse F39.4 Purified Hu C, ICC/IF, P, WB
1 ml / €340.00
  IgG1   Acris Antibodies GmbH
 
DM245

Androgen receptor antibody

Formalin fixed paraffin embedded human prostate stained with Androgen Receptor antibody DM245 Mouse AR441 Purified Can, Hu C, P, WB
1 ml / €510.00
  IgG1   Acris Antibodies GmbH
 
DM245-05

Androgen receptor antibody

Formalin fixed paraffin embedded human prostate stained with Androgen Receptor antibody DM245 Mouse AR441 Purified Can, Hu C, P, WB
0.5 ml / €350.00
  IgG1   Acris Antibodies GmbH
 
SM5020P

Androgen receptor antibody

Figure 1 shows immunolocalization of androgen receptor in primate brain using SM5020P Rat AN1-15 Purified Hu, Ms, Prim, Rt C, ICC/IF, IP, P, WB
50 µg / €380.00
  IgG   Acris Antibodies GmbH
 

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