Antibodies to NPY Receptors (NPYR) - FocusOn 001

Introduction

Neuropeptide Y (NPY) is a neuropeptide colocalized and abundantly released with the neurotransmitter norepinephrine in the nervous system. It is synthesized by the postnatal olfactory epithelium of sustentacular cells. It promotes the proliferation of postnatal neuronal precursor cells and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion and potent vasoactive effects on the cardiovascular system.

Neuropeptide Y family of peptides signal through a family of G protein-coupled receptors present in the brain and sympathetic neurons. These NPY receptors (Y1-Y6) recognize NPY and related peptides.

Antibody Tools for detections of NPY Receptors Type 1 – 6 and Y2

Acris Antibodies offers an antibody panel to all six NPY receptors. These antibodies are useful for the detection of Neuropeptide Y Receptors by Western blotting; some of them can be used in immunohistochemical methods.

Available antibodies to NPY Receptor

Neuropeptide Y Receptor 1 antibody (NPY1R), Neuropeptide Y Receptor 2 (NPY2R), Neuropeptide Y Receptor 3 (NPY3R), Neuropeptide Y Receptor 4 (NPY4R), Neuropeptide Y Receptor 5 (NPY5R), Neuropeptide Y Receptor 6 (NPY6R), Neuropeptide Y Receptor Pan (NPY Receptor), Neuropeptide Y Y2 Receptor (NPYY2R).

For specificity confirmation control peptides are available to use with NPYR1 , NPYR2, NPYR3, NPYR4, NPYR5 and NPYR6 antibody.