Antibodies to VIP Receptors - FocusOn 044

Introduction: The Vasoactive Intestinal Peptide (VIP) is expressed and secreted by neurons innervating primary and secondary immune organs such as lymph nodes. VIP is a potent neurotrophic factor.

It causes vasodilation, lowers arterial blood pressure, and relaxes the smooth muscles of trachea, stomach and gall bladder. VIP also modulates several T-lymphocyte activities including motility, cytokine production, proliferation and apoptosis. VIP exerts its biological activity by binding to two closely related class II G-protein-coupled receptors (VPAC-1&2). Beside this VIP has its own receptors VIPR1&2.

The VIP receptors (VIPR) are integral membrane proteins mainly expressed in lung, liver, kidney, heart and placenta. They belong to the family 2 of G-protein coupled receptors. The expression of VIPR is regulated by multiple transcription factors including VIPRRP.

Antibody Tools for the Specific Detection of VIP Receptor 1 & 2 and VIPRPR

Acris Antibodies offers a panel of monoclonal and polyclonal antibodies to VIPR1/2 and VIP Receptor - gene Repressor Protein (VIPRRP) suitable for immunological detection methods like western blotting or immunohistochemistry.

Available Antibody Panel to VIP Receptors

VIP Receptor 1 (VIPR 1) antibody, VIP Receptor 2 (VIPR 2) antibody, VIP Receptor - gene Repressor Protein (VIPRRP) antibody