Product Description for KCNQ2
Rabbit anti Human, Mouse, Rat KCNQ2.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence.
Properties for KCNQ2
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | KQT-like 2, KvLQT2, Neuroblastoma-specific potassium channel subunit alpha KvLQT2, Potassium voltage-gated channel subfamily KQT member 2, Voltage-gated potassium channel subunit Kv7.2 |
| Presentation | Aff - Purified |
| Reactivity | Hu, Ms, Rt |
| Applications | C, ICC/IF |
| Clonality | Polyclonal |
| Host | Rabbit |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
| Material safety datasheet | MSDS for Polyclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Antibody type | Ab |
| Application | Immunocytochemistry: 0.5 µg/ml. Immunohistochemistry on frozen sections: 0.5 µg/ml, staining of rat hippocampal using SP5352P yielded a strong signal in granule cell layer and the mossy fibers found in the central hilus of the dentate gyrus. Immunofluorescence: 0.5 µg/ml. Western Blot. |
| Background | KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KNCQs (KCNQ1-5) found in the central nervous system and KNCQ2 and 3 have demonstrated their importance in M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy. |
| Concentration | 1.0 mg/ml |
| General Readings |
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| Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format |
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| Specificity |
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| Gene ID | 3785 |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for KCNQ2 (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00003785-P01-10 |
KCNQ2 |
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Human | in vitro transl. |
10 µg /
€350.00
|
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| Abnova Taiwan Corp. | |||||||
| H00003785-P01-25 |
KCNQ2 |
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Human | in vitro transl. |
25 µg /
€500.00
|
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| Abnova Taiwan Corp. | |||||||
Positive controls for KCNQ2 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00003785-T01 |
KCNQ2 Lysate(Denatured) |
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0.1 ml /
€240.00
|
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| Abnova Taiwan Corp. | |||||||
Recommended Secondary Antibodies for KCNQ2 (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
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|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
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|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||






