Product Description for ABCD2 Lysate
Product is tested for Western blot / Immunoblot.
Properties for ABCD2 Lysate
| Product Category | Lysates |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | ABC39, ALDL1, ALDR, ALDRP, hALDR |
| Shipping to | Not USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Novus Biologicals Inc. |
Datasheet Extract
| Add. information | This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes. |
|---|---|
| Application | Western Blot, This product is intended for use as a positive control in Western Blot., Western Blot |
| Background | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Concentration | 1 mg/ml |
| Storage | Store at -20C. Avoid freeze-thaw cycles. |
| Targets |
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