Properties for 17-DMAG
| Product Category | Others |
|---|---|
| Quantity | 1 mg |
| Shipping to | Not USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Novus Biologicals Inc. |
Datasheet Extract
| Add. information | Synthetic 17-DMAG Soluble in DMSO (>25mg/mL) and ethanol (10mg/mL) Purple solid |
|---|---|
| Application | , Synthetic 17-DMAG Soluble in DMSO (>25mg/mL) and ethanol (10mg/mL) Purple solid |
| Background | 17-DMAG is a water soluble & cell-permeable analog of Geldanamycin and 17-AAG (1). It binds to the APTase site of human Hsp90a with high affinity, has cytotoxic activity against many cancer cell lines (2), and acts as angiogenesis inhibitor (3). This Hsp90 inhibitor shows promise in preclinical models. 17-DMAG has excellent bioavailability, is widely distributed to tissues, and is quantitatively metabolized much less than is 17-AAG. |
| General Readings |
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| Storage | Store at -20C. Avoid freeze-thaw cycles. |





