Product Description for 14-3-3 protein beta/alpha
Properties for 14-3-3 protein beta/alpha
|Synonyms||FocusOn116, KCIP-1, Protein 1054, Protein kinase C inhibitor protein 1, YWHAB|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Purity||> 90 %|
|Background||The 14-3-3 family plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3 beta, a subtype of the 14-3-3 proteins, was found in B Cells, brain and liver etc. This 14-3-3 beta has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery.|
|General Readings||Rodriguez LG., et al. (2005). J Cell Physiol. Jan; 202(1):285-94.
Mils V., et al.(2000). Oncogene. Mar 2; 19(10):1257-65.
|Storage||Store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
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