Product Description for 14-3-3 protein beta/alpha
14-3-3 protein beta/alpha.
Presentation: Purified
Presentation: Purified
Properties for 14-3-3 protein beta/alpha
| Product Category | Proteins |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | FocusOn116, KCIP-1, Protein 1054, Protein kinase C inhibitor protein 1, YWHAB |
| Presentation | Purified |
| Molecular weight | kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % |
| Background | The 14-3-3 family plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3 beta, a subtype of the 14-3-3 proteins, was found in B Cells, brain and liver etc. This 14-3-3 beta has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. |
| Concentration | 1.0 mg/ml |
| General Readings | Rodriguez LG., et al. (2005). J Cell Physiol. Jan; 202(1):285-94. Mils V., et al.(2000). Oncogene. Mar 2; 19(10):1257-65. |
| Storage | Store (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Description |
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| Format |
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| FocusOn and Reviews | |
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