AR09099PU-N 14-3-3 protein beta/alpha (1-246)

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0.1 mg / €370.00
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14-3-3 protein beta/alpha

AR09099PU-N

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Product Description for 14-3-3 protein beta/alpha

14-3-3 protein beta/alpha.
Presentation: Purified

Properties for 14-3-3 protein beta/alpha

Product Category Proteins
Quantity 0.1 mg
Synonyms KCIP-1, Protein 1054, Protein kinase C inhibitor protein 1, YWHAB
Presentation Purified
Molecular weight kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P31946
Purity > 90 %
Background The 14-3-3 family plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3 beta, a subtype of the 14-3-3 proteins, was found in B Cells, brain and liver etc. This 14-3-3 beta has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery.
Concentration 1.0 mg/ml
General Readings Rodriguez LG., et al. (2005). J Cell Physiol. Jan; 202(1):285-94.
Mils V., et al.(2000). Oncogene. Mar 2; 19(10):1257-65.
Storage Store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant Human 14-3-3 beta was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MTMDKSELVQ KAKLAEQAER YDDMAAAMKA VTEQGHELSN EERNLLSVAY KNVVGARRSS WRVISSIEQK TERNEKKQQM GKEYREKIEA ELQDICNDVL ELLDKYLIPN ATQPESKVFY LKMKGDYFRY LSEVASGDNK QTTVSNSQQA YQEAFEISKK EMQPTHPIRL GLALNFSVFY YEILNSPEKA CSLAKTAFDE AIAELDTLNE ESYKDSTLIM QLLRDNLTLW TSENQGDEGD AGEGEN
Molecular weight:
(246 aa)
Format
Buffer System:
20 mM Tris pH 8.0, 1 mM EDTA, 50 mM NaCl
Purity:
>90% pure by SDS-PAGE
State:
Liquid purified protein
Purified
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