14-3-3 protein epsilon - NBC1-18392

Product Description for 14-3-3 protein epsilon

14-3-3 protein epsilon.

Immunogen	Swiss Prot Num: P62258
Application	Western Blot, Useful in Western Blot, Western Blot
Background	The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, ?, ?, ?, ?, ?, ? and ? that have been identified in mammals. The 14-3-3 epsilon, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Recombinant human 14-3-3 ? was expressed in E.coli and purified by using conventional chromatography techniques.
Concentration	1 mg/ml
Storage	Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Format	Buffer System: No Preservative Purity: Protein
FocusOn and Reviews	FocusOns: Antibody Panel to Proteins of the 14-3-3 family (14-3-3 beta, 14-3-3 gamma, 14-3-3 epsilon, 14-3-3 zeta, 14-3-3 theta, 14-3-3 sigma, 14-3-3 eta) - FocusOn 116
Targets	14-3-3 protein epsilon antibody