Product Description for Alpha-Synuclein / SNCA
Alpha-Synuclein / SNCA.
Properties for Alpha-Synuclein / SNCA
|Synonyms||FocusOn131, NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, PARK1|
|Molecular weight||14.516 kDa|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Purity||> 95 %|
|Add. information||Real molecular weight on SDS-PAGE will be shift up (see picture below).|
|Background||Alpha-Synuclein, an acidic neuronal protein, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. Alpha-Synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Moreover, recent studies have shown that alpha-synuclein has chaperone activity and that this activity is lost upon removing its C-terminal acidic tail (amino acids 96-140).|
|Storage||Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.