BMP2 / BMP2A - DA3502X | acris-antibodies.com

Product Description for BMP2 / BMP2A

BMP2 / BMP2A.
Presentation: Purified

Product Category	Proteins
Quantity	25 µg
Synonyms	BMP-2, BMP-2A, Bone morphogenetic protein 2
Presentation	Purified
Molecular weight	26 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	Acris Antibodies GmbH

Immunogen	Swiss Prot Num: P12643
Purity	> 95 %
Background	Human Bone Morphogenetic Protein-2 (BMP-2) is a disulfide-bonded homodimeric protein with an apparent molecular weight of 26 kDa. BMP-2 regulates similiarly to its nearest homologue BMP-4 diverse fundamental processes during embryonic development: BMP-2 and other BMP proteins have great potential for medical therapeutic applications, in particular because they allow or at least accelerate the ossification of extensive bone lesions. BMP-2 is a heparin binding protein.
General Readings	Wozney et al., Science 242:1528, 1988. Ruppert et al., Eur J Biochem 237:295, 1996.
Storage	Lyophilized samples are stable for 6 months from despatch at -20°C to -70°C. Reconstituted BMP-2 should be stored in working aliquots at -20°C. Avoid repeated freezing and thawing.
Description	Biological activity: Measured by the ability of BMP-2 to induce Alkaline Phosphatase production by C2C12 myogenic cells. The ED50 for this effect is typically 0.3-0.8 µg/ml. Specific activity: 2.5 x 10³ units/mg
Format	Buffer System: 50mM Acetic Acid Stabilizers: None Endotoxin level: < 0.1 ng per µg of BMP-2 Purity: pure by SDS-PAGE and visualised by silver stain State: Lyophilized purified Ig fraction Purified Reconstitution: The lyophilized BMP-2 is best soluble in 50 mM Acetic Acid and at a concentration of 0.1 mg/ml but should be also soluble in most aqueous buffers when the pH is below 6.0
Targets	BMP2 / BMP2A antibody