Product Description for HSPB1 / HSP27
HSPB1 / HSP27.
Properties for HSPB1 / HSP27
|Synonyms||28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, HSP25, HSP28, Heat shock 27 kDa protein, Heat shock protein beta-1, Review 003, SRP27, Stress-responsive protein 27|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Proteins (de)|
|Purity||> 95 %|
|Background||Hsp27 (also known as the Estrogen-Regulated 24K protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38).|
|Concentration||1.0 mg/ml (determined by Bradford assay)|
|General Readings||Friedman MJ., et al. (2009) J Biol Chem. 284(41):27944-51.
Brunet Simioni M., et al. (2009) Oncogene. 28(37):3332-44.
|Storage||Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.