HSPB1 / HSP27 (1-205, His-tag) - AR09327PU-L

Product Description for HSPB1 / HSP27

HSPB1 / HSP27.
Presentation: Purified

Product Category	Proteins
Quantity	0.5 mg
Synonyms	28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, HSP25, HSP28, Heat shock 27 kDa protein, Heat shock protein beta-1, Review 003, SRP27, Stress-responsive protein 27
Presentation	Purified
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	Acris Antibodies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P04792
Purity	> 95 %
Background	Hsp27 (also known as the Estrogen-Regulated 24K protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38).
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	Friedman MJ., et al. (2009) J Biol Chem. 284(41):27944-51. Brunet Simioni M., et al. (2009) Oncogene. 28(37):3332-44.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	AA Sequence: `MGSSHHHHHH SSGLVPRGSH MTERRVPFSL LRGPSWDPFR DWYPHSRLFD QAFGLPRLPE EWSQWLGGSS WPGYVRPLPP AAIESPAVAA PAYSRALSRQ LSSGVSEIRH TADRWRVSLD VNHFAPDELT VKTKDGVVEI TGKHEERQDE HGYISRCFTR KYTLPPGVDP TQVSSSLSPE GTLTVEAPMP KLATQSNEIT IPVTFESRAQ LGGPEAAKSD ETAAK`
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) contining 1 mM DTT, 10% glycerol Endotoxin level: < 1.0 EU per 1 µg of protein (determined by LAL method ) Purity: >95% by SDS - PAGE State: Liquid purified protein Purified
Targets	HSPB1 / HSP27 antibody