Product Description for Interleukin-6 (IL6)
Properties for Interleukin-6 (IL6)
|Synonyms||B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFNB2, IL-6, Interferon beta-2|
|Molecular weight||21.7 kDa|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Purity||> 98 %|
|Add. information||Centrifuge the vial prior to opening.|
|Background||IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R alpha and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells.|
|Storage||The lyophilized protein is stable at -20°C for one year from despatch.
The reconstituted IL-6 is stable for three months when stored in working aliquots with a carrier protein at -20°C.
Avoid repeated freezing and thawing.