Product Description for SRC peptide-pTyr418 (phospho and non-phospho pair)
SRC peptide-pTyr418 (phospho and non-phospho pair).
Properties for SRC peptide-pTyr418 (phospho and non-phospho pair)
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|Background||Src (also known as pp60src) is a non-receptor tyrosine kinase involved in signal transduction in many biological systems and implicated in the development of human tumors. Tyrosine 418 is located in the catalytic domain and is one of the autophosphorylation sites. Full catalytic activity of Src requires phosphorylation of tyrosine 418 (tyrosine 414 on frog Src, tyrosine 416 on chicken Src, and tyrosine 424 on mouse Src). This region of Src is also highly conserved in all of the related Src-family kinases, and thus prior immunoprecipitation may be required to identify which Src family member is being activated.|