Product Description for RAD17
Rabbit anti Bovine, Equine, Human, Monkey, Mouse RAD17.
Properties: pSer645
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.
Properties: pSer645
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.
Properties for RAD17
| Product Category | Antibodies |
|---|---|
| Quantity | 20 µg |
| Synonyms | Cell cycle checkpoint protein RAD17, R24L, RF-C/activator 1 homolog |
| Presentation | Aff - Purified |
| Reactivity | Bov, Eq, Hu, Mky, Ms |
| Applications | P, WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
| Material safety datasheet | MSDS for Polyclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Property | pSer645 |
| Antibody type | Ab |
| Application | Immunohistochemistry on paraffin sections: 5 µg/ml. Western blot: 0.025-1 µg/ml. |
| Background | Rad17, also known as 'cell cycle checkpoint protein RAD17,' is a nuclear protein belonging to the Rad17/RAD24 family and necessary for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Rad17 is known to have a weak ATPase activity and is required for binding to chromatin and also participates in the recruitment of the RAD1-RAD9-HUS1 complex onto chromatin, and in CHEK1 activation. It may also serve as a sensor of DNA replication progression, and may be involved in homologous recombination. Rad17 is a part of a DNA-binding complex containing RFC2, RFC3, RFC4 and RFC5. Four isoforms have been reported by X-ray irradiation. Overexpression of this protein is seen in various cancer cell lines and in colon carcinoma. |
| Concentration | 0.2 mg/ml |
| General Readings |
|
| Storage | Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format |
|
| Species Reactivity |
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| Specificity |
|
| Gene ID | 5884 |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for RAD17 (3 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00005884-P01 |
RAD17 |
||||||
 |
Human | Purified |
2 µg /
€250.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00005884-Q01-10 |
RAD17 |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00005884-Q01-25 |
RAD17 |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for RAD17 (3 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00005884-T01 |
RAD17 293T Cell Transient Overexpression Lysate(Denatured) |
||||||
|
0.1 ml /
€240.00
|
||||||
| Abnova Taiwan Corp. | |||||||
| NBL1-15111 |
Rad17 Lysate |
||||||
![Western Blot: Rad17 Lysate [NBL1-15111] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for RAD17](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Rad17 Lysate-Western Blot-NBL1-15111-img0001.jpg) |
0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
| NBL1-15112 |
Rad17 Lysate |
||||||
![Western Blot: Rad17 Lysate [NBL1-15112] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for RAD17](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Rad17 Lysate-Western Blot-NBL1-15112-img0001.jpg) |
0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for RAD17 (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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