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Product Description for CD158d / KIR2DL4
Killer cell immunoglobulin-like receptor 2DL4, MHC class I NK cell receptor KIR103AS, Killer cell inhibitory receptor 103AS, CD158 antigen-like family member D
Properties for CD158d / KIR2DL4
| Manufacturer | Acris Antibodies GmbH |
| Quantity | 0.1 ml |
| Reactivity | Human |
| Presentation | Purified |
| Applications | Enzyme Immunoassay, Western blot / Immunoblot |
| Isotype | IgG2b |
| Host | Mouse |
| Clone | 2H6 |
| Shipping to | Worldwide |
Datasheet Extract
| Synonyms | KIR103AS, G9P, FocusOn037, FocusOn114 |
| Swiss Prot Num | Q99706 |
| Immunogen | Recombinant human KIR2DL4 purified from E. coli |
| Product Type | Antibodies |
| Recommended Isotype Control | SM12P, AM03110PU-N |
| Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Shin JS, Shin EC, Kim J, Choi IH, Park JH, Kim SJ. 1999. Monoclonal antibodies with various reactivity to p58 killer inhibitory receptors. Hybridoma 18:521-527. 2. Chwae YJ, Chang MJ, Park SM, Yoon H, Park HJ, Kim SJ, Kim J. 2002 Molecular mechanism of the activation-induced cell death inhibition mediated by a p70 inhibitory killer cell Ig-like receptor in Jurkat T cells. J Immunology 169:3726-3735. |
| Format | State: Liquid purified Ig fraction |
| Purification: Protein A affinity chromatography | |
| Buffer System: PBS, pH 7.4, containing 0.09 % sodium azide | |
| Specificity | This antibody recognizes KIR2DL1, KIR2DL3, KIR2DL4 and KIR2DS4, members of killer cell immunoglobulin-like receptor family: ELISA KIR2DL1: ++ KIR2DL3: + KIR2DL4: +++ KIR2DS4: ++ Western blot (1:500 - 1:2,000) KIR2DL1: +++ KIR2DL3: +++ KIR2DL4: ++ KIR2DS4: ++ |
| Application | ELISA. Western blot. |
| Background | The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human NK cells and a subset of human T cells which they are involved in recognition of either MHC class I molecules or unknown ligand on target cells and inhibit cytotoxic activities. |
| Concentration | 1.0 mg/ml |
| Focuson | 037 Antibodies to NK-cells: CD335 (NKp46), CD305 (LAIR-1) and KIR – Family |
| Focuson | 114 NK-Cell Markers |
Secondary Antibodies for CD158d / KIR2DL4
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / 190 Euro | |||||
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / 170 Euro | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / 160 Euro | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / 180 Euro | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / 170 Euro | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment | ||||||
| Rabbit | PE | 1 ml / 290 Euro | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment | ||||||
| Goat | PE | 1 ml / 290 Euro | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / 290 Euro | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / 270 Euro | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / 250 Euro | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / 250 Euro | |||||
