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Product Description for 5-HT1F / HTR1F
5HT (Serotonin) 1F Receptor
Properties for 5-HT1F / HTR1F
| Manufacturer | Acris Antibodies GmbH |
| Quantity | 50 µg |
| Reactivity | Human, Mouse, Rat |
| Presentation | Aff - Purified |
| Applications | Paraffin Sections |
| Host | Rabbit |
| PDF datasheet | view  |
| Shipping to | Not USA/Canada |
Datasheet Extract
| Synonyms | 5-Hydroxytryptamine Receptor 1F, Serotonin Receptor 1F, 5-HT-1F, HTR1EL, FocusOn042 |
| Swiss Prot Num | P30939 |
| Immunogen | Synthetic peptide - KLH conjugated Epitope: 3rd cytoplasmic domain of human |
| Product Type | Antibodies |
| Immunogen | Swiss Prot Num: P30939 |
| Genename: HTR1F | |
| Remarks: The immunizing peptide shows 94 % identity (94 % similarity) with mouse and 94 % identity (94 % similarity) with rat. | |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format | State: Liquid Ig fraction |
| Purification: Peptide immunogen affinity column | |
| Buffer System: PBS, pH 7.7, containing 0.01% sodium azide | |
| Specificity | Reacts to Serotonin Receptor 1F. (Family: GPCR, Subfamily: Serotonin) |
| Add. information | This product was originally produced by MBL International. |
| Application | Immunohistochemsiry on paraffin embedded sections: 6-9 µg/ml. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Background | 5-HT1F, a Serotonin Receptor, is negatively coupled to adenylate cyclase. Selective 5-HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors. Expression of the 5-HT1F receptor has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen. |
| Concentration | 1 mg/ml |
| Focuson | 042 Antibodies to 5-hydroxytryptamine (Serotonin) Receptors |
Secondary Antibodies for 5-HT1F / HTR1F
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / 190 Euro | |||||
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / 160 Euro | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / 160 Euro | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / 170 Euro | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / 160 Euro | |||||
| R1427R | Rabbit IgG F(ab)2 Fragment | ||||||
| Donkey | PE | 1 ml / 290 Euro | |||||
| R1458C2 | Rabbit IgG (H&L) | ||||||
| Goat | Cy2 | 1 mg / 250 Euro | |||||
| R1458C3 | Rabbit IgG (H&L) | ||||||
| Goat | Cy3 | 1 mg / 250 Euro | |||||
| R1458C5 | Rabbit IgG (H&L) | ||||||
| Goat | Cy5 | 1 mg / 250 Euro | |||||
