11-beta HSD1 / HSD11B1 antibody
Principal name
11-beta HSD1 / HSD11B1 antibody
Alternative names for 11-beta HSD1 / HSD11B1 antibody
11-beta-hydroxysteroid dehydrogenase 1, HSD11, HSD11L, 11-DH, Corticosteroid 11-beta-dehydrogenase isozyme 1
Selected pictures


SwissProt ID
P16232 (Rat), P28845 (Human), P50172 (Mouse), P51975 (Sheep), Q6QLL4 (Cavpo), Q7M3I4 (Rabit)
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)
Background of 11-beta HSD1 / HSD11B1 antibody
HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, HSD11B1 can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children.The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.
General readings
Paterson JM, Morton NM, Fievet C, Kenyon CJ, Holmes MC, Staels B, Seckl JR, Mullins JJ. Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice. Proc Natl Acad Sci U S A. 2004 May 4;101(18):7088-93. Epub 2004 Apr 26. PMID: 15118095
Antibodies
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| 10928-1-AP |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Rabbit | Aff - Purified | Hu | E, WB |
0.15 ml /
€255.00
|
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| IgG | ProteinTech Group, Inc. | ||||||
| AP16309PU-N |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Goat | Aff - Purified | Bov, Chimp, Hu, Sh | WB |
0.1 mg /
€270.00
|
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| Acris Antibodies GmbH | |||||||
| AP31570PU-N |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Goat | Aff - Purified | Ms, Rt | E, WB |
0.1 mg /
€270.00
|
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| Acris Antibodies GmbH | |||||||
| AP31830PU-N |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Rabbit | Aff - Purified | Hu, Ms, Rt | P, WB |
50 µl /
€380.00
|
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| IgG | Acris Antibodies GmbH | ||||||
| NB300-934 |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Goat | Aff - Purified | Hu | E, WB |
0.1 mg /
€370.00
|
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| IgG | Novus Biologicals Inc. | ||||||
| NB300-934PEP |
11-beta HSD1 / HSD11B1 Control Peptide | ||||||
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E |
0.1 mg /
€280.00
|
|||||
| Novus Biologicals Inc. | |||||||
| NBP1-32027 |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Rabbit | Hu | ICC/IF, P, WB |
0.1 mg /
€390.00
|
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| IgG | Novus Biologicals Inc. | ||||||
+1 additional image | |||||||
| NBP1-69644 |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Rabbit | Aff - Purified | Hu, Ms, Rt | WB |
50 µg /
€390.00
|
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| Novus Biologicals Inc. | |||||||
| GTX104626 |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Rabbit | Aff - Purified | Hu | ICC/IF, WB |
0.1 ml /
€340.00
|
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| GeneTex Inc. | |||||||
| GTX113741 |
11-beta HSD1 / HSD11B1 (119-266) antibody | ||||||
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Rabbit | Aff - Purified | Hu | WB |
0.1 ml /
€230.00
|
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| GeneTex Inc. | |||||||
| H00003290-A01 |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Mouse | Serum | Hu | E |
50 µl /
€260.00
|
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| Abnova Taiwan Corp. | |||||||
| H00003290-B01P |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Mouse | Purified | Hu | E(detection), WB |
50 µg /
€340.00
|
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| Abnova Taiwan Corp. | |||||||
+1 additional image | |||||||
| H00003290-D01P |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Rabbit | Purified | Hu | E(detection), WB |
0.1 mg /
€360.00
|
||
| Abnova Taiwan Corp. | |||||||
+1 additional image | |||||||
| H00003290-M02A |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Mouse | 2C10 | Ascites | Hu | E, WB |
0.2 ml /
€340.00
|
|
| IgM | Abnova Taiwan Corp. | ||||||
| PAB6723 |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Goat | Bov, Hu, Mky, Sh | E, WB |
0.1 mg /
€330.00
|
|||
| Abnova Taiwan Corp. | |||||||
| ARP45714_P050 |
11-beta HSD1 / HSD11B1 antibody | ||||||
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Rabbit | Aff - Purified | African clawed frog, Bov, Can, Hu, Ms, Por, Rb, Rt | P, WB |
50 µg /
€330.00
|
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| AVIVA Systems Biology | |||||||
+2 additional images | |||||||
Proteins
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00003290-P01-10 |
11-beta HSD1 / HSD11B1 | ||||||
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Human | in vitro transl. |
10 µg /
€350.00
|
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| Abnova Taiwan Corp. | |||||||
| H00003290-P01-25 |
11-beta HSD1 / HSD11B1 | ||||||
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Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Lysates
| Catalog No. | Name | ||||||
|---|---|---|---|---|---|---|---|
| H00003290-T01 |
HSD11B1 293T Cell Transient Overexpression Lysate(Denatured) | ||||||
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0.1 ml /
€240.00
|
||||||
| Abnova Taiwan Corp. | |||||||
| NBL1-11718 |
HSD11B1 Lysate | ||||||
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0.1 mg /
€370.00
|
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| Novus Biologicals Inc. | |||||||






![Immunofluorescence: HSD11B1 Antibody [NBP1-32027]-analysis of HeLa, using HSD11B1 antibody at 1:200 dilution.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/110457_2.jpg)
+1 additional image![Western Blot: HSD11B1 Antibody [NBP1-69644] - This Anti-HSD11B1 antibody was used in Western Blot of Fetal Liver tissue lysate at a concentration of 1ug/ml.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/HSD11B1 Antibody-Western Blot-NBP1-69644-img0001.jpg)





![Western Blot: HSD11B1 Lysate [NBL1-11718] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for HSD11B1](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/HSD11B1 Lysate-Western Blot-NBL1-11718-img0001.jpg)