14-3-3 protein epsilon antibody
Principal name
14-3-3 protein epsilon antibody
Alternative names for 14-3-3 protein epsilon antibody
14-3-3E, YWHAE, FocusOn116
Selected pictures


SwissProt ID
P62258 (Human), P62259 (Mouse), P62260 (Rat), P62261 (Bovin), P62262 (Sheep), Q5ZMT0 (Chick)
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F), Frozen Sections (C)
Background of 14-3-3 protein epsilon antibody
14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 beta, gamma, episilon, zeta, eta, theta and sigma. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities.
General readings
1. Martin, H. et al. (1993) Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein. FEBS 331: 296-303.
2. Aitken, A. et al. (2006) 14-3-3 proteins: A historic overview. Seminars in Cancer Biology 16: 162-172.
3. Wang, Z. et al. (2011) The prognostic value of 14-3-3 isoforms in vulvar squamous cell carcinoma cases: 14-3-3ß and e are independent prognostic factors for these tumors. PLoS One. 6: e24843.
Antibodies
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| AM09042PU-N |
14-3-3 protein epsilon antibody | ||||||
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Mouse | 5A5 | Purified | Hu, Ms | E, P, WB |
0.1 ml /
€310.00
|
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| IgG2a | Acris Antibodies GmbH | ||||||
+3 additional images | |||||||
| AM09042PU-S |
14-3-3 protein epsilon antibody | ||||||
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Mouse | 5A5 | Purified | Hu, Ms | E, P, WB |
Regular Price: 50 µl / €230.00 Special Price: 50 µl / €161.00 |
|
| IgG2a | Acris Antibodies GmbH | ||||||
+3 additional images | |||||||
| AP05565SU-N |
14-3-3 protein epsilon (C-term) antibody | ||||||
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Rabbit | Serum | Bov, Chk, Hu, Ms, Rb, Rt, Sh | E, P, WB |
0.1 ml /
€430.00
|
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| IgG | Acris Antibodies GmbH | ||||||
| AP05568SU-N |
14-3-3 protein epsilon antibody | ||||||
![]() |
Rabbit | Serum | Bov, Chk, Hu, Ms, Rb, Rt, Sh | E, P, WB |
0.1 ml /
€430.00
|
||
| IgG | Acris Antibodies GmbH | ||||||
+1 additional image | |||||||
| AP06766PU-N |
14-3-3 protein epsilon antibody | ||||||
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Rabbit | Aff - Purified | Hu, Ms, Rt | E, ICC/IF, P, WB |
0.1 mg /
€320.00
|
||
| Acris Antibodies GmbH | |||||||
+1 additional image | |||||||
| AP12543CP-N |
14-3-3 protein epsilon control peptide | ||||||
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0.1 mg /
€120.00
|
||||||
| Acris Antibodies GmbH | |||||||
| AP12544CP-N |
14-3-3 protein epsilon control peptide | ||||||
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0.1 mg /
€120.00
|
||||||
| Acris Antibodies GmbH | |||||||
| AP22883SU-N |
14-3-3 protein epsilon (N-term) antibody | ||||||
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Rabbit | Serum | Sh | E, P, WB |
50 µl /
€380.00
|
||
| Acris Antibodies GmbH | |||||||
| AP32388PU-N |
14-3-3 protein epsilon pSer185 antibody | ||||||
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Sheep | Aff - Purified | Bov, Hu, Ms, Rb, Rt, Sh | WB |
0.1 ml /
€340.00
|
||
| IgG | Acris Antibodies GmbH | ||||||
| NB100-92415 |
14-3-3 protein epsilon antibody | ||||||
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Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
€370.00
|
||
| IgG | Novus Biologicals Inc. | ||||||
| NBP1-22960 |
14-3-3 protein epsilon antibody | ||||||
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Mouse | 5A5 | Purified | Hu | E, SDS-PAGE, WB |
0.1 ml /
€340.00
|
|
| IgG2a | Novus Biologicals Inc. | ||||||
| NBP1-32695 |
14-3-3 protein epsilon antibody | ||||||
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Rabbit | Hu, Ms | ICC/IF, P, WB |
0.1 ml /
€390.00
|
|||
| IgG | Novus Biologicals Inc. | ||||||
+2 additional images | |||||||
| NBP1-33554 |
14-3-3 protein epsilon antibody | ||||||
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Rabbit | Hu | ICC/IF, P, WB |
0.1 ml /
€390.00
|
|||
| IgG | Novus Biologicals Inc. | ||||||
| NBP1-68205-0.1 |
14-3-3 protein epsilon antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | E, WB |
0.1 mg /
€340.00
|
||
| IgG | Novus Biologicals Inc. | ||||||
| NBP1-68205-50 |
14-3-3 protein epsilon antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | E, WB |
50 µg /
€290.00
|
||
| IgG | Novus Biologicals Inc. | ||||||
| NBP1-89827 |
14-3-3 protein epsilon antibody | ||||||
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Rabbit | Aff - Purified | Hu | C, ICC/IF, P, WB |
0.1 ml /
€360.00
|
||
| IgG | Novus Biologicals Inc. | ||||||
+2 additional images | |||||||
| GTX82193 |
14-3-3 protein epsilon antibody | ||||||
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Chicken | Aff - Purified | Bov, Hu, Ms, Rt | WB |
50 µg /
€460.00
|
||
| GeneTex Inc. | |||||||
| GTX109090 |
14-3-3 protein epsilon antibody | ||||||
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Rabbit | Aff - Purified | Hu | ICC/IF, P, WB |
0.1 ml /
€300.00
|
||
| GeneTex Inc. | |||||||
| GTX113576 |
14-3-3 protein epsilon antibody | ||||||
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Rabbit | Aff - Purified | Hu | WB |
0.1 ml /
€300.00
|
||
| GeneTex Inc. | |||||||
| H00007531-A01 |
14-3-3 protein epsilon antibody | ||||||
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Mouse | Serum | Hu | E, WB |
50 µl /
€260.00
|
||
| Abnova Taiwan Corp. | |||||||


+3 additional images




![Western Blot: 14-3-3 episilon Antibody [NB100-92415] - Western blot (WB) analysis of 14-3-3 å (D238) antibody in extracts from HepG2 cells.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/p_92415_1.jpg)
![Immunohistochemistry: 14-3-3 epsilon Antibody [NBP1-32695] - analysis of paraffin-embedded A549 xenograft , using 14-3-3 epsilon antibody at 1:500 dilution.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/111115_2.jpg)
![Western Blot: 14-3-3 epsilon Antibody [NBP1-33554] – Western blot analysis of 14-3-3 epsilon on H1299 lysates using NBP1-33554 at a dilution of 1:1000. 30ug whole cell lysate loaded on 12% SDS PAGE gel.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/111886_1.jpg)
![Western Blot: 14-3-3 epsilon Antibody [NBP1-89827] Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11 | Lane 2: RT-4 | Lane 3: U-251 MG | Lane 4: Human Plasma | Lane 5: Liver | Lane 6: Tonsil](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/14-3-3 epsilon Antibody-Western Blot-NBP1-89827-0005.jpg)