14-3-3 protein epsilon antibody

Principal name

14-3-3 protein epsilon antibody

Alternative names for 14-3-3 protein epsilon antibody

14-3-3E, YWHAE

Selected pictures

14-3-3 protein epsilon antibody - AP06766PU-N
AP06766PU-N - Western blot analysis of AP06766PU-N 14-3-3 ε antibody in extracts from HepG2 cells.
14-3-3 protein epsilon antibody - AP06766PU-N
AP06766PU-N - Immunohistochemistry analyzes of AP06766PU-N 14-3-3 ε antibody in Paraffin-Embedded Human brain tissue.

SwissProt ID

P62258 (Human), P62259 (Mouse), P62260 (Rat), P62261 (Bovin), P62262 (Sheep), Q5ZMT0 (Chick)

Gene ID

7531 (YWHAE), 22627 (Ywhae)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Rb (Rabbit), Sh (Sheep), Can (Canine), Ze (Zebrafish), African clawed frog

Available hosts

Mouse, Rabbit, Chicken, Sheep

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of 14-3-3 protein epsilon antibody

14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 beta, gamma, episilon, zeta, eta, theta and sigma. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities.

General readings

Oriente F, et al.(2005) J Biol Chem. ;280(49):40642-9.
Conklin D, et al.(2005) PNAS ,92(17):7892-7896.

2 Item(s)

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Antibodies

Catalog No. Host Clone/Iso. Pres. React. Applications  
AM09042PU-N

14-3-3 protein epsilon antibody

Western blot analysis: The extracts of mouse brain (50 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human 14-3-3 epsilon (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse 5A5 Purified Hu, Ms E, P, WB
0.1 ml / €310.00
  IgG2a   Acris Antibodies GmbH
 
AM09042PU-S

14-3-3 protein epsilon antibody

Western blot analysis: The extracts of mouse brain (50 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human 14-3-3 epsilon (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse 5A5 Purified Hu, Ms E, P, WB

Regular Price: 50 µl / €230.00

Special Price: 50 µl / €161.00

  IgG2a   Acris Antibodies GmbH
 

2 Item(s)

per page
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