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14-3-3 protein eta antibody

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Principal name

14-3-3 protein eta antibody

Alternative names for 14-3-3 protein eta antibody

Protein AS1, YWHAH, YWHA1, FocusOn116

Selected pictures

14-3-3 protein eta antibody - 15222-1-AP 14-3-3 protein eta
15222-1-AP 14-3-3 protein eta - Human brain were subjected to SDS PAGE followed by western blot with 15222-1-AP(YWHAH Antibody) at dilution of 1:1000
14-3-3 protein eta antibody - AP20467PU-N
AP20467PU-N - Western blot (WB) analysis of 14-3-3 theta pAb in extracts from Jurkat cells.

SwissProt ID

P68509 (Bovin), P68510 (Mouse), P68511 (Rat), Q04917 (Human)

Gene ID

7533 (YWHAH)

Ncbi ID

NP_003396.1, NP_003396, 9606

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Rb (Rabbit), Sh (Sheep)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C)

Background of 14-3-3 protein eta antibody

14-3-3 eta is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for its different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein.
14-3-3 eta is expressed principally in the brain although it is expressed at low levels in other tissues. The protein binds alphasynuclein, forming part of lewy bodies in parkinsons disease and has been linked to earlyonset schizophrenia. The eta isoform binds both gremlin 1, which is overexpressed in human cancers, and the DAL1/Protein 4.1B tumour suppressor. Furthermore the glucocortcoid receptor is positively regulated by 14-3-3eta.
AHP1046 may not react with recombinant proteins that are not Nacetylated.

General readings

Shigeto Sato., et al. (2006), EMBO. 25, 211-221.
Chen J., et al. (2007), J Neurosci Res. 85(8):1724-33.

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Antibodies

Catalog No. Host Clone/Iso. Pres.   React. Applications  
AP05566SU-N

14-3-3 protein eta antibody

Western blots of 14-3-3 isoforms in HEK293 cell extracts using 14-3-3 antibodies. Lane 1: anti-gamma 14-3-3 (AP05567SU-N) Lane 2: anti-zeta 14-3-3 (AP05572SU-N) Lane 3: anti-C-epsilon-14-3-3 (AP05565SU-N) Lane 4: anti-N-epsilon-14-3-3 (AP05568SU-N) Lane 5: anti-eta 14-3-3. (AP05566SU-N) The 14-3-3 isoforms run at 30kDa except epsilon 14-3-3 Rabbit Serum Bov, Chk, Hu, Ms, Rb, Rt, Sh P, WB
0.1 ml / €430.00
  IgG   Acris Antibodies GmbH
 
AP22684SU-N

14-3-3 protein eta (N-term) antibody

Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with YWHAH antibody AP22684SU-N at 1/250 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Serum Bov, Chk, Hu, Ms, Rb, Rt, Sh P, WB
50 µl / €380.00
  IgG   Acris Antibodies GmbH
+1 additional image
 
AP32434SU-N

14-3-3 protein eta (N-term) antibody

14-3-3 protein eta Rabbit Serum Bov, Chk, Hu, Ms, Rb, Rt, Sh C, WB
0.1 ml / €350.00
    Acris Antibodies GmbH
 

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