14-3-3 protein gamma antibody
Principal name
14-3-3 protein gamma antibody
Alternative names for 14-3-3 protein gamma antibody
YWHAG, KCIP-1, FocusOn116 , Protein kinase C inhibitor protein 1
Selected pictures


SwissProt ID
P61981 (Human), P61982 (Mouse), P61983 (Rat), P68252 (Bovin), P68253 (Sheep), Q5F3W6 (Chick)
Gene ID
7532 (YWHAG)
Ncbi ID
Available reactivities
Available hosts
Available applications
Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection))
Background of 14-3-3 protein gamma antibody
14-3-3 gamma is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for its different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein.
14-3-3 gamma is thought to play an important role in muscle, being induced by growth factors in human vascular smooth muscle cells, and being expressed in skeletal and heart muscles. An example is the gamma isoform binds musclespecific receptor tyrosine kinase regulating synaptic gene transmission. The gamma isoform binds amyloid betaprotein precursor intracellular domain fragment (AICD) and FE65, facilitating FE65dependent gene transactivation. The binding of 14-3-3 gamma to glial fibrillary acidic protein is important in the regulation of glial filaments. 14-3-3 gamma binds and may regulate CDK11 during the cell cycle and apoptosis. The gamma isoform is lowered in foetal Downs syndrome brains.
General readings
1. Martin, H. et al. (1993) Antibodies against major brain isoforms of 14-3-3 protein. An antibody specific for the Nacetylated aminoterminus of a protein. FEBS 331: 296 - 303.
2. Aitken, A. et al. (2006) 14-3-3 proteins: A historic overview. Seminars in Cancer Biology 16: 162 - 172.
3. Wang, Z. et al. (2011) The prognostic value of 14-3-3 isoforms in vulvar squamous cell carcinoma cases: 14-3-3ß and e are independent prognostic factors for these tumors.
PLoS One. 6: e24843.
Antibodies
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| 12381-1-AP |
14-3-3 protein gamma antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms | E, WB |
0.15 ml /
€255.00
|
||
| IgG | ProteinTech Group, Inc. | ||||||
+1 additional image | |||||||
| AM09044PU-N |
14-3-3 protein gamma antibody | ||||||
![]() |
Mouse | J3H10 | Purified | Hu, Ms | E, WB |
0.1 ml /
€310.00
|
|
| IgG2b | Acris Antibodies GmbH | ||||||
+3 additional images | |||||||
| AM09044PU-S |
14-3-3 protein gamma antibody | ||||||
![]() |
Mouse | J3H10 | Purified | Hu, Ms | E, WB |
50 µl /
€230.00
|
|
| IgG2b | Acris Antibodies GmbH | ||||||
+3 additional images | |||||||
| AM26569AF-N |
14-3-3 protein gamma (1-12) antibody | ||||||
![]() |
Mouse | KC21 | Azide Free | Hu, Ms, Rt | IP, WB |
0.1 mg /
€290.00
|
|
| IgG2a | Acris Antibodies GmbH | ||||||
+1 additional image | |||||||
| AM32791PU-N |
14-3-3 protein gamma (incl. pos. control) antibody | ||||||
![]() |
Mouse | CG31-2B6 | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€360.00
|
|
| Acris Antibodies GmbH | |||||||
| AP05567SU-N |
14-3-3 protein gamma antibody | ||||||
![]() |
Rabbit | Serum | Bov, Chk, Hu, Ms, Rt, Sh | E, P, WB |
0.1 ml /
€430.00
|
||
| IgG | Acris Antibodies GmbH | ||||||
| AP17846CP-N |
14-3-3 protein gamma Control Peptide | ||||||
![]() |
0.1 mg /
€120.00
|
||||||
| Acris Antibodies GmbH | |||||||
| AP17846PU-N |
14-3-3 protein gamma antibody | ||||||
![]() |
Rabbit | Hu, Ms | E, WB |
0.1 mg /
€330.00
|
|||
| Acris Antibodies GmbH | |||||||
| AP17847CP-N |
14-3-3 protein gamma Control Peptide | ||||||
![]() |
0.1 mg /
€120.00
|
||||||
| Acris Antibodies GmbH | |||||||
| AP17847PU-N |
14-3-3 protein gamma (N-term) antibody | ||||||
![]() |
Rabbit | Hu, Ms | E, WB |
0.1 mg /
€330.00
|
|||
| Acris Antibodies GmbH | |||||||
| AP20539PU-N |
14-3-3 protein gamma antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
€320.00
|
||
| Acris Antibodies GmbH | |||||||
+1 additional image | |||||||
| NB100-406 |
14-3-3 protein gamma (N-term modified) antibody | ||||||
![]() |
Mouse | KC21 | Ascites | Hu | WB |
0.1 ml /
€330.00
|
|
| IgG2a | Novus Biologicals Inc. | ||||||
| NB100-406SS |
14-3-3 protein gamma antibody | ||||||
![]() |
Mouse | KC21 | Hu | WB |
25 µl /
€150.00
|
||
| IgG2a | Novus Biologicals Inc. | ||||||
| NB100-407 |
14-3-3 protein gamma (N-term modified) antibody | ||||||
![]() |
Mouse | HS23 | Ascites | Hu | WB |
0.1 ml /
€320.00
|
|
| IgG2a | Novus Biologicals Inc. | ||||||
+1 additional image | |||||||
| NB100-407SS |
14-3-3 protein gamma antibody | ||||||
![]() |
Mouse | HS23 | Ascites | Bov, Chk, Hu, Ms, Rt, Ze | ICC/IF, WB |
25 µl /
€170.00
|
|
| IgG1 | Novus Biologicals Inc. | ||||||
| NBP1-19694 |
14-3-3 protein gamma antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
€370.00
|
||
| Novus Biologicals Inc. | |||||||
| NBP1-68207-0.1 |
14-3-3 protein gamma antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | E, ICC/IF, P, WB |
0.1 mg /
€340.00
|
||
| IgG | Novus Biologicals Inc. | ||||||
| NBP1-68207-50 |
14-3-3 protein gamma antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | E, ICC/IF, P, WB |
50 µg /
€290.00
|
||
| IgG | Novus Biologicals Inc. | ||||||
| NBP1-74584 |
14-3-3 protein gamma antibody | ||||||
![]() |
Mouse | Purified | Hu | E, IP, WB |
0.1 mg /
€320.00
|
||
| IgG1 | Novus Biologicals Inc. | ||||||
| GTX14117 |
14-3-3 protein gamma antibody | ||||||
![]() |
Mouse | 3F8 | Purified | Hu | IP, WB |
0.25 ml /
€360.00
|
|
| IgG | GeneTex Inc. | ||||||


+1 additional image








![Immunocytochemistry: 14-3-3 gamma Antibody (HS23) [NB100-407] - Detection of 14-3-3 gamma (green) in HepG2 cells using NB100-407. Nuclei (Blue) are counterstained with Hoechst 33258.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/89363_1.jpg)
![Western Blot: 14-3-3 gamma Antibody (See Label) [NBP1-74584] - Hela Cell lysate stained by Msx14.3.3 gamma at 1:200](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/14-3-3 gamma Antibody (See Label)-Western Blot-NBP1-74584-img0001.jpg)