14-3-3 protein zeta/delta antibody
Principal name
14-3-3 protein zeta/delta antibody
Alternative names for 14-3-3 protein zeta/delta antibody
YWHAZ, KCIP-1, FocusOn116 , Protein kinase C inhibitor protein 1
Selected pictures
-Western-Blot-NB100-1964-img0001.jpg)

SwissProt ID
P29361 (Sheep), P63101 (Mouse), P63102 (Rat), P63103 (Bovin), P63104 (Human), Q5ZKC9 (Chick), Q91896 (Xenla)
Gene ID
7534 (YWHAZ)
Ncbi ID
Available reactivities
Available hosts
Available applications
Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Radial Immunodiffusion (RID), ELISA (detection) (E(detection))
Background of 14-3-3 protein zeta/delta antibody
It is a member of the 14-3-3 family which consists of 30kDa proteins that are involved in multiple protein kinase signaling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for its different isotypes and are regulated by phosphorylation of both 14-3-3 and the bound protein. 14-3-3 zeta is a susceptibility gene for paranoid schizophrenia and is overexpressed in the temporal cortex of cognitively impared Alzheimers patients. The protein binds yeast Sps1/Ste20-related kinase 1 (YSK1) and localizes to the golgi, possibly linking YSK1 signaling, protein transport, cell adhesion and migration. It co-localizes with epidermal growth factor receptor to the plasma membrane following epidermal growth factor signaling. The zeta isoform is involved in MAPKAPK2-mediated phosphorylation which may have a role in p38 MAPK-dependent inflammation. When bound to ADAM 22, 14-3-3 zeta is involved in cell adhesion. 14-3-3 zeta also interacts with cofilin, LIM-domain-containing protein kinase 1, protein kinase B/Akt and GPI alpha.
General readings
Choi EK et al. Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2. J Biol Chem 276:19197-204 (2001).
Antibodies
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| 14881-1-AP |
14-3-3 protein zeta/delta antibody | ||||||
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Rabbit | Aff - Purified | Hu, Ms | E, WB |
0.15 ml /
€255.00
|
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| IgG | ProteinTech Group, Inc. | ||||||
| AP02457PU-N |
14-3-3 protein zeta/delta pSer58 antibody | ||||||
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Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
Regular Price: 0.1 mg / €320.00 Special Price: 0.1 mg / €256.00 |
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| Acris Antibodies GmbH | |||||||
+2 additional images | |||||||
| AP02457PU-S |
14-3-3 protein zeta/delta pSer58 antibody | ||||||
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Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
Regular Price: 50 µg / €240.00 Special Price: 50 µg / €192.00 |
||
| Acris Antibodies GmbH | |||||||
+2 additional images | |||||||
| AP02701PU-N |
14-3-3 protein zeta/delta antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms | P, WB |
Regular Price: 0.1 mg / €270.00 Special Price: 0.1 mg / €216.00 |
||
| Acris Antibodies GmbH | |||||||
+1 additional image | |||||||
| AP02701PU-S |
14-3-3 protein zeta/delta antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms | P, WB |
Regular Price: 50 µg / €230.00 Special Price: 50 µg / €184.00 |
||
| Acris Antibodies GmbH | |||||||
+1 additional image | |||||||
| AP05572SU-N |
14-3-3 protein zeta/delta (N-term acetylated) antibody | ||||||
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Rabbit | Serum | Bov, Chk, Hu, Ms, Rt, Sh | E, P, WB |
0.1 ml /
€430.00
|
||
| IgG | Acris Antibodies GmbH | ||||||
| AP06623PU-N |
14-3-3 protein zeta/delta antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms | E, P, WB |
0.1 mg /
€320.00
|
||
| Acris Antibodies GmbH | |||||||
+1 additional image | |||||||
| AP07437PU-N |
14-3-3 protein zeta/delta pSer58 antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | P, WB |
50 µg /
€380.00
|
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| IgG | Acris Antibodies GmbH | ||||||
| AP08195PU-N |
14-3-3 protein zeta/delta antibody | ||||||
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Rabbit | Aff - Purified | Hu, Ms, Rt | P, WB |
50 µg /
€380.00
|
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| IgG | Acris Antibodies GmbH | ||||||
| AP15151PU-N |
14-3-3 protein zeta/delta antibody | ||||||
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Rabbit | Aff - Purified | Hu | E, P, WB |
0.1 mg /
€330.00
|
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| Ig | Acris Antibodies GmbH | ||||||
+1 additional image | |||||||
| AP15332PU-M |
14-3-3 protein zeta/delta (134-149) antibody | ||||||
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Rabbit | Purified | Hu, Ms, Rt | P, WB |
0.5 ml /
€290.00
|
||
| Acris Antibodies GmbH | |||||||
+1 additional image | |||||||
| AP15332PU-N |
14-3-3 protein zeta/delta (134-149) antibody | ||||||
![]() |
Rabbit | Purified | Hu, Ms, Rt | P, WB |
1 ml /
€400.00
|
||
| Acris Antibodies GmbH | |||||||
+1 additional image | |||||||
| AP15332PU-S |
14-3-3 protein zeta/delta (134-149) antibody | ||||||
![]() |
Rabbit | Purified | Hu, Ms, Rt | P, WB |
0.1 ml /
€170.00
|
||
| Acris Antibodies GmbH | |||||||
+1 additional image | |||||||
| AP20192PU-N |
14-3-3 protein zeta/delta antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, IP, P, WB |
0.1 mg /
€320.00
|
||
| Acris Antibodies GmbH | |||||||
+1 additional image | |||||||
| AP20468PU-N |
14-3-3 protein zeta/delta antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | P, WB |
0.1 mg /
€320.00
|
||
| Acris Antibodies GmbH | |||||||
+1 additional image | |||||||
| AP21526PU-N |
14-3-3 protein zeta/delta (50-100) antibody | ||||||
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Rabbit | Purified | Bov, Can, Hu, Mky, Ms, Op, Por | P, WB |
0.1 mg /
€310.00
|
||
| Acris Antibodies GmbH | |||||||
+1 additional image | |||||||
| AP21527PU-N |
14-3-3 protein zeta/delta (200-245) antibody | ||||||
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Rabbit | Purified | Bov, Can, Hu, Mky, Ms, Rt | WB |
0.1 mg /
€310.00
|
||
| Acris Antibodies GmbH | |||||||
| AP54747SU-N |
14-3-3 protein zeta/delta pSer184 antibody | ||||||
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Rabbit | Serum | Hu, Ms, Rt | E, P, WB |
0.2 ml /
€380.00
|
||
| Acris Antibodies GmbH | |||||||
| NB100-81766 |
14-3-3 protein zeta/delta pSer58 antibody | ||||||
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Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
€340.00
|
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| IgG | Novus Biologicals Inc. | ||||||
+2 additional images | |||||||
| NB100-91646 |
14-3-3 protein zeta/delta antibody | ||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, IP, P, WB |
0.1 mg /
€370.00
|
||
| IgG | Novus Biologicals Inc. | ||||||
+1 additional image | |||||||



+2 additional images











![Immunohistochemistry: 14-3-3 zeta Phosphospecific Antibody [NB100-81766] - Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using 14-3-3 æ (Phospho-Ser58) antibody](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/p_81766_1.jpg)
![Western Blot: 14-3-3 zeta Antibody [NB100-91646] - Western blot (WB) analyzes of 14-3-3 zeta (V52) antibody in extracts from 293 cells.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/p_91646_1.jpg)