17-beta HSD6 / HSD17B6 antibody

Principal name

17-beta HSD6 / HSD17B6 antibody

Alternative names for 17-beta HSD6 / HSD17B6 antibody

Oxidative 3-alpha hydroxysteroid dehydrogenase, RODH, Hydroxysteroid 17-beta dehydrogenase 6, 3-alpha->beta-hydroxysteroid epimerase

Selected pictures

17-beta HSD6 / HSD17B6 antibody - 11855-1-AP 17-beta HSD6 / HSD17B6
11855-1-AP 17-beta HSD6 / HSD17B6 - Immunohistochemistry of paraffin-embedded Lung cancer using 11855-1-AP(HSD17B6 Antibody) at Dilution 1:50 (under 10x lens)
17-beta HSD6 / HSD17B6 antibody - 11855-1-AP 17-beta HSD6 / HSD17B6
11855-1-AP 17-beta HSD6 / HSD17B6 - Human liver were subjected to SDS PAGE followed by western blot with 11855-1-AP(HSD17B6 Antibody) at dilution of 1:1200

SwissProt ID

O14756 (Human), O54753 (Rat), Q3T001 (Bovin), Q9R092 (Mouse)

Gene ID

8630 (HSD17B6)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of 17-beta HSD6 / HSD17B6 antibody

HSD17B6 has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. HSD17B6 is a member of the retinol dehydrogenase family.The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.

General readings

Ewens, K.G., et al. J. Clin. Endocrinol. Metab. (2010) In press
Jones, M.R., et al. J. Clin. Endocrinol. Metab. 94(12):5034-5038(2009)
Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009)  
Belyaeva, O.V., et al. Endocrinology 148(5):2148-2156(2007)
Jones, M.R., et al. Fertil. Steril. 86(5):1438-1446(2006)
Chetyrkin, S.V., et al. Arch. Biochem. Biophys. 386(1):1-10(2001)
Kedishvili, N.Y., et al. Chem. Biol. Interact. 130-132 (1-3), 457-467 (2001)

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Antibodies

Catalog No. Host Clone/Iso. Pres.   React. Applications  
11855-1-AP

17-beta HSD6 / HSD17B6 antibody

Immunohistochemistry of paraffin-embedded Lung cancer using 11855-1-AP(HSD17B6 Antibody) at Dilution 1:50 (under 10x lens) Rabbit Aff - Purified Hu E, P, WB
0.15 ml / €255.00
  IgG   ProteinTech Group, Inc.
 
AP52113PU-N

17-beta HSD6 / HSD17B6 (N-term) antibody

Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with 17-beta HSD6 / HSD17B6 Antibody (N-term) Cat.-No AP52113PU-N, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Aff - Purified Hu E, P, WB
0.1 mg / €330.00
  Ig   Acris Antibodies GmbH
 
NBP1-31672

17-beta HSD6 / HSD17B6 antibody

Western Blot: HSD17B6 Antibody [NBP1-31672] - Western blot on Molt-4, diluted at 1:1000. Rabbit Hu P, WB
0.1 ml / €390.00
  IgG   Novus Biologicals Inc.
 
NBP1-56686

17-beta HSD6 / HSD17B6 antibody

Western Blot: HSD17B6 Antibody [NBP1-56686] - This Anti-HSD17B6 antibody was used in Western Blot of A172 tissue lysate at a concentration of 1.25ug/ml. Rabbit Purified Bov, Can, Hu, Ms, Rt P, WB
0.1 mg / €330.00
    Novus Biologicals Inc.
 
GTX109009

17-beta HSD6 / HSD17B6 antibody

17-beta HSD6 / HSD17B6 Rabbit Aff - Purified Hu WB
0.1 ml / €300.00
    GeneTex Inc.
 
H00008630-B01P

17-beta HSD6 / HSD17B6 antibody

Western Blot analysis of HSD17B6 expression in transfected 293T cell line (H00008630-T01) by HSD17B6 MaxPab polyclonal antibody.

Lane 1: HSD17B6 transfected lysate(34.87 KDa).
Lane 2: Non-transfected lysate.
Mouse Purified Hu E(detection), WB
50 µg / €340.00
    Abnova Taiwan Corp.
 
ARP41529_T100

17-beta HSD6 / HSD17B6 antibody

17-beta HSD6 / HSD17B6 Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt P, WB
0.1 mg / €290.00
    AVIVA Systems Biology
 

Proteins

Catalog No. Species Pres. Purity   Source  
H00008630-P01-10

17-beta HSD6 / HSD17B6

17-beta HSD6 / HSD17B6 Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
 
H00008630-P01-25

17-beta HSD6 / HSD17B6

17-beta HSD6 / HSD17B6 Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.
 
H00008630-Q01-10

17-beta HSD6 / HSD17B6

17-beta HSD6 / HSD17B6 Human Purified
10 µg / €350.00
  Abnova Taiwan Corp.
 
H00008630-Q01-25

17-beta HSD6 / HSD17B6

17-beta HSD6 / HSD17B6 Human Purified
25 µg / €500.00
  Abnova Taiwan Corp.
 

Lysates

Catalog No. Name  
H00008630-T01

HSD17B6 293T Cell Transient Overexpression Lysate(Denatured)

HSD17B6 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €240.00
  Abnova Taiwan Corp.
 
NBL1-11729

HSD17B6 Lysate

Western Blot: HSD17B6 Lysate [NBL1-11729] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for HSD17B6.  
0.1 mg / €370.00
  Novus Biologicals Inc.
 

13 Item(s)

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