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ABCC11 / MRP8 antibody

Principal name

ABCC11 / MRP8 antibody

Alternative names for ABCC11 / MRP8 antibody

ATP-binding cassette transporter sub-family C member 11

Selected pictures

H00085320-B01P - ABCC11 MaxPab polyclonal antibody. Western Blot analysis of ABCC11 expression in HepG2.

H00085320-B01P - Western Blot analysis of ABCC11 expression in transfected 293T cell line (H00085320-T02) by ABCC11 MaxPab polyclonal antibody.Lane 1: ABCC11 transfected lysate(60.83 KDa).Lane 2: Non-transfected lysate.

SwissProt ID

Q96J66 (Human)

Gene ID

85320 (ABCC11)

Ncbi ID

9606, NP_115972, NP_149163, NP_115972.2

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine)

Available hosts

Mouse, Goat, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Frozen Sections (C), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of ABCC11 / MRP8 antibody

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene.

General readings

1. ABCC10, ABCC11, and ABCC12. Kruh GD, Guo Y, Hopper-Borge E, Belinsky MG, Chen ZS. Pflugers Arch. 2007 Feb;453(5):675-84
2. cGMP transport by vesicles from human and mouse erythrocytes. de Wolf CJ, Yamaguchi H, van der Heijden I, Wielinga PR, Hundscheid SL, Ono N, Scheffer GL, de Haas M, Schuetz JD, Wijnholds J, Borst P. FEBS J. 2007 Jan;274(2):439-50
3. MRP8/ABCC11 directly confers resistance to 5-fluorouracil. Oguri T, Bessho Y, Achiwa H, Ozasa H, Maeno K, Maeda H, Sato S, Ueda R. Mol Cancer Ther. 2007 Jan;6(1):122-7
4. Gene expression profiling of ATP-binding cassette (ABC) transporters as a predictor of the pathologic response to neoadjuvant chemotherapy in breast cancer patients. Park S, Shimizu C,
5. Shimoyama T, Takeda M, Ando M, Kohno T, Katsumata N, Kang YK, Nishio K, Fujiwara Y. Breast Cancer Res Treat. 2006 Sep;99(1):9-17.
6. A SNP in the ABCC11 gene is the determinant of human earwax type. Yoshiura K, Kinoshita A, Ishida T, et al. Nat Genet. 2006 Mar;38(3):324-30.

16 products - FILTER YOUR RESULTS!

Antibodies

Catalog No.	Host	Clone/Iso.	Pres.	React.	Applications
AM31991SU-N	ABCC11 / MRP8 antibody
	Rat	M8I-74	Supernatant	Hu	C, ICC/IF, WB	1 ml / €410.00
		IgG				Acris Antibodies GmbH

AP16811PU-N	ABCC11 / MRP8 antibody
	Goat		Aff - Purified	Bov, Can, Hu	E, WB	0.1 mg / €270.00
						Acris Antibodies GmbH

NBP1-20944	ABCC11 / MRP8 antibody
	Goat		Aff - Purified	Hu	E, WB	0.1 mg / €370.00
		IgG				Novus Biologicals Inc.

NBP1-59810	ABCC11 / MRP8 antibody
	Rabbit		Aff - Purified	Hu	WB	50 µg / €390.00
						Novus Biologicals Inc.

NBP1-82623	ABCC11 / MRP8 antibody
	Rabbit		Aff - Purified	Hu	C, P	0.1 ml / €360.00
		IgG				Novus Biologicals Inc.

H00085320-B01	ABCC11 / MRP8 antibody
	Mouse		Serum	Hu	E(detection), WB	50 µl / €340.00
						Abnova Taiwan Corp.
+1 additional image

H00085320-B01P	ABCC11 / MRP8 antibody
	Mouse		Purified	Hu	E(detection), WB	50 µg / €340.00
						Abnova Taiwan Corp.
+1 additional image

H00085320-D01	ABCC11 / MRP8 antibody
	Rabbit		Serum	Hu	E(detection), IP	0.1 ml / €360.00
						Abnova Taiwan Corp.

H00085320-M02	ABCC11 / MRP8 antibody
	Mouse	4H6	Purified	Hu	E, WB	0.1 mg / €340.00
		IgG2a				Abnova Taiwan Corp.

PAB11553	ABCC11 / MRP8 antibody
	Goat				E, WB	0.1 mg / €330.00
						Abnova Taiwan Corp.

ARP43719_P050	ABCC11 / MRP8 antibody
	Rabbit		Aff - Purified	Hu	WB	50 µg / €330.00
						AVIVA Systems Biology

Proteins

Catalog No.	Species	Pres.
H00085320-P01	ABCC11 / MRP8
	Human	Purified	2 µg / €250.00
			Abnova Taiwan Corp.

H00085320-Q01-10	ABCC11 / MRP8
	Human	Purified	10 µg / €350.00
			Abnova Taiwan Corp.

H00085320-Q01-25	ABCC11 / MRP8
	Human	Purified	25 µg / €500.00
			Abnova Taiwan Corp.

Lysates

Catalog No.	Name
H00085320-T01	ABCC11 293T Cell Transient Overexpression Lysate(Denatured)
		0.1 ml / €240.00
		Abnova Taiwan Corp.

Antibody Pairs

Catalog No.	Name
H00085320-PW1	ABCC11 (Human) IP-WB Antibody Pair
		1 set / €710.00
		Abnova Taiwan Corp.