Alternative names for ABHD4 antibody
Alpha/beta-hydrolase 4, Abhydrolase domain-containing protein 4, Lyso-N-acylphosphatidylethanolamine lipase
Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C), Western blot / Immunoblot (WB)
Background of ABHD4 antibody
Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.