Home » Target » ABI3 antibody

ABI3 antibody

Principal name

ABI3 antibody

Alternative names for ABI3 antibody

NESH, ABI gene family member 3

Selected pictures

AP50031PU-N - ABI3 Antibody (N-term) (Cat. #AP50031PU-N) western blot analysis in K562 cell line lysates (35 µg/lane).This demonstrates the ABI3 antibody detected the ABI3 protein (arrow).

AP50031PU-N - ABI3 Antibody (N-term) (Cat. #AP50031PU-N) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

SwissProt ID

Q8BYZ1 (Mouse), Q9P2A4 (Human)

Gene ID

51225 (ABI3)

Ncbi ID

9606, NP_001128658, NP_057512.1

Available reactivities

Hu (Human)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of ABI3 antibody

ABI3, also as known as ABI gene family member 3, belongs to the ABI family. This protein is a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain. The Abi family members are thought to negatively regulate cell growth and transformation, including cellular transformation through v-Abl as well as mediate cell motility by regulating actin polymerization in lamellipodia and filopodia. ABI3 inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase.

General readings

1. Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
2. Hirao, N., et al. FEBS Lett. 580(27):6464-6470(2006)
3. Ichigotani, Y., et al. Int. J. Mol. Med. 9(6):591-595(2002)
4. Ichigotani, Y., et al. Cancer Res. 62(8):2215-2219(2002)
5. Matsuda, S., et al. J. Hum. Genet. 46(8):483-486(2001)

Antibodies

Catalog No.	Host	Clone/Iso.	Pres.	React.	Applications
AP50031PU-N	ABI3 (N-term) antibody
	Rabbit		Aff - Purified	Hu	E, WB	0.1 mg / €330.00
		Ig				Acris Antibodies GmbH
+1 additional image