Switch to Acris Antibodies Inc. (North America) Switch to Acris Antibodies GmbH (Europe/Worldwide)
Home » Target » MMP-8 antibody

MMP-8 antibody

(reset)

Principal name

MMP-8 antibody

Alternative names for MMP-8 antibody

Neutrophil collagenase, Matrix metalloproteinase-8, PMNL collagenase, MMP8, CLG1, PMNL-CL, Review 001

Selected pictures

MMP-8 antibody - H00004317-B01
H00004317-B01 - Western Blot analysis of MMP8 expression in transfected 293T cell line (H00004317-T01) by MMP8 MaxPab polyclonal antibody.Lane 1: MMP8 transfected lysate(51.37 KDa).Lane 2: Non-transfected lysate.
MMP-8 antibody - H00004317-B01
H00004317-B01 - MMP8 MaxPab polyclonal antibody. Western Blot analysis of MMP8 expression in human liver.

SwissProt ID

O70138 (Mouse), O88766 (Rat), P22894 (Human)

Gene ID

4317 (MMP8), 63849 (Mmp8)

Ncbi ID

NP_002415.1, 9606, 5874, 10116, NP_002415, NP_071557

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Dot blot (Dot), Radial Immunodiffusion (RID)

Background of MMP-8 antibody

Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase and collagenase 2. MMP8 degrades fibrillar collagens types I, II, III, aggrecan, serpins and alpha 2 macroglobulin. All collagenases cleave fibrillar collagens at one specific site resulting in generation of N terminal three quarter and C terminal one quarter fragments, which then denature to gelatin at body temperature. The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen. MMP13, in turn degrades type II collagen 6 fold more efficiently than type I and type II collagens and displays almost 50 fold stronger gelatinolytic activity than MMP1 and MMP8. MMP8 is very similar to MMP1, sharing 57 % amino acid identity. Most cell types do not produce MMP8. Until recently, it was thought that MMP8 was produced exclusively by neutrophils, but it has also been detected in other cell types including arthritic chondrocytes and gingival fibroblasts. The human MMP8 gene has the chromosomal location of 11q22.2-22.3. MMP8 is heavily glycosylated, and the zymogen has a mass of 85 Kd. The zymogen is quickly activated to the 64 Kd form, and this breaks down to a cascade of active forms.

General readings

1. Van den Steen, P.E., et al., Biochem. Biophys. Res. Commun. 310(3):889-896 (2003).
2. Giambernardi, T.A., et al., Matrix Biol. 20(8):577-587 (2001).
3. Nagase, H., et al., J. Biol. Chem. 274(31):21491-21494 (1999).
4. Massova, I., et al., FASEB J. 12(12):1075-1095 (1998).
5. Pendas, A.M., et al., Genomics 37(2):266-268 (1996).

Items 1 to 20 of 40 total

per page
Page:
  1. 1
  2. 2
40 products - FILTER YOUR RESULTS!

Antibodies

Catalog No. Host Clone/Iso. Pres.   React. Applications  
17874-1-AP

MMP-8 antibody

Immunohistochemistry of paraffin-embedded H-placenta using 17874-1-AP(MMP8 Antibody) at Dilution 1:100 (under 10x lens) Rabbit Aff - Purified Hu, Ms E, WB
0.15 ml / €255.00
  IgG   ProteinTech Group, Inc.
+2 additional images
 
AF8310

MMP-8 antibody

MMP-8 Mouse 115-13D2 Purified Hu C, E, P, WB
0.1 mg / €360.00
  IgG1   Acris Antibodies GmbH
 
AP05868PU-N

MMP-8 (C-term) antibody

MMP-8 Rabbit Purified Hu C, WB
0.1 mg / €470.00
  IgG   Acris Antibodies GmbH
 
AP06235PU-N

MMP-8 antibody

Figure 1. Western blot(WB) analysis of MMP-8 antibody in extracts from NIH/3T3 cells. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €320.00
    Acris Antibodies GmbH
+1 additional image
 
AP07218PU-N

MMP-8 antibody

Heart: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Purified Hu, Mky, Ms, Rt E, P, WB
50 µg / €380.00
    Acris Antibodies GmbH
 
AP13186CP-N

MMP-8 Control Peptide

MMP-8
0.1 mg / €120.00
    Acris Antibodies GmbH
 
AP13186PU-N

MMP-8 antibody

Western blot analysis of anti-MMP8 Pab in mouse liver tissue lysate (35ug/lane). MMP8 (arrow) was detected using the purified Pab Rabbit Purified Hu, Ms E, P, WB
0.1 mg / €330.00
  Ig   Acris Antibodies GmbH
+1 additional image
 
AP23348PU-N

MMP-8 (N-term) antibody

MMP8 Polyclonal Antibody Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €340.00
  IgG   Acris Antibodies GmbH
+1 additional image
 
AP26349PU-N

MMP-8 antibody

MMP-8 Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €320.00
    Acris Antibodies GmbH
 
NB100-91880

MMP-8 antibody

Immunohistochemistry: MMP-8 Antibody [NB100-91880] - Immunohistochemistry (IHC) analyzes of MMP-8 (F445) antibody in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €370.00
  IgG   Novus Biologicals Inc.
+1 additional image
 
NB110-60989

MMP-8 antibody

Immunohistochemistry-Paraffin: MMP8 Antibody (MM0023-7A11) [NB110-60989] - Human placenta (formalin fixed and paraffin embedded) section is subjected to IHC. Mouse MM0023-7A11 Purified Hu P, WB
0.1 mg / €390.00
  IgG2   Novus Biologicals Inc.
 
NBP1-41498

MMP-8 antibody

MMP-8 Rabbit Hu, Ms, Rt P, WB
0.1 mg / €340.00
  IgG   Novus Biologicals Inc.
 
NBP1-67640-0.1

MMP-8 antibody

MMP-8 Rabbit Aff - Purified Hu, Ms, Rt C, E, WB
0.1 mg / €340.00
  IgG   Novus Biologicals Inc.
 
NBP1-67640-50

MMP-8 antibody

MMP-8 Rabbit Aff - Purified Hu, Ms, Rt C, E, WB
50 µg / €290.00
  IgG   Novus Biologicals Inc.
 
NBP1-85576

MMP-8 antibody

Western Blot: MMP8 Antibody [NBP1-85576] Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11 | Lane 2: RT-4 | Lane 3: U-251 MG | Lane 4: Human Plasma | Lane 5: Liver | Lane 6: Tonsil Rabbit Aff - Purified Hu C, P, WB
0.1 ml / €360.00
  IgG   Novus Biologicals Inc.
+1 additional image
 
NBP1-85577

MMP-8 antibody

Immunohistochemistry-Paraffin: MMP8 Antibody [NBP1-85577] Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in subsets of cells in the red pulp. Rabbit Aff - Purified Hu C, P
0.1 ml / €360.00
  IgG   Novus Biologicals Inc.
 
GTX11607

MMP-8 antibody

MMP-8 Rabbit Aff - Purified Hu C, E, IP, WB
25 µg / €280.00
  IgG   GeneTex Inc.
 
GTX11608

MMP-8 antibody

MMP-8 Rabbit Aff - Purified Hu E, IP, WB
50 µg / €320.00
  IgG   GeneTex Inc.
 
GTX113780

MMP-8 antibody

Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE GTX113780 diluted at 1:500 Rabbit Aff - Purified Hu Dot
0.1 ml / €300.00
    GeneTex Inc.
 
H00004317-B01

MMP-8 antibody

Western Blot analysis of MMP8 expression in transfected 293T cell line (H00004317-T01) by MMP8 MaxPab polyclonal antibody. Lane 1: MMP8 transfected lysate(51.37 KDa). Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €340.00
    Abnova Taiwan Corp.
+1 additional image
 

Items 1 to 20 of 40 total

per page
Page:
  1. 1
  2. 2

Filter Options

Product Type
  1. Antibodies (33)
  2. Antibody Pairs (1)
  3. Kits (3)
  4. Lysates (1)
  5. Proteins (2)
Antibody type
  1. Antibody (Ab) (32)
  2. Control peptide (Ab/CP) (1)
Clonality
  1. Polyclonal (31)
  2. Monoclonal (2)
Target
  1. MMP-8 (35)
Property
  1. C-term (1)
  2. Hinge Region (1)
  3. N-term (1)
Reactivity
  1. Human (Hu) (32)
  2. Mouse (Ms) (16)
  3. Rat (Rt) (14)
  4. Monkey (Mky) (2)
Applications
  1. Western blot / Immunoblot (WB) (30)
  2. Paraffin Sections (P) (16)
  3. Enzyme Immunoassay (E) (15)
  4. Frozen sections (C) (9)
  5. Immunoprecipitation (IP) (6)
  6. ELISA (detection) (E(detection)) (4)
  7. Dot blot (Dot) (1)
  8. RID (1)
Presentation
  1. Aff - Purified (16)
  2. Purified (10)
  3. Serum (2)
Host
  1. Rabbit (28)
  2. Mouse (4)
Images
  1. 1 image (18)
  2. 3+ images (1)
Images: Applications
  1. Paraffin Sections (P) (13)
  2. Western blot / Immunoblot (WB) (13)
Species (Protein)
  1. Human (2)
Manufacturer
  1. Acris Antibodies GmbH (8)
  2. Abnova Taiwan Corp. (13)
  3. Novus Biologicals Inc. (7)
  4. Young In Frontier Co. Ltd. (4)
  5. GeneTex Inc. (3)
  6. Assay Biotech (2)
  7. AbboMax Inc (1)
  8. ProteinTech Group, Inc. (1)
  9. QED Bioscience Inc. (1)
Service
 
© Copyright 1998 - 2013 Acris Antibodies GmbH