Thrombospondin-1 (THBS1) antibody

Principal name

Thrombospondin-1 (THBS1) antibody

Alternative names for Thrombospondin-1 (THBS1) antibody

TSP, TSP1

Selected pictures

Thrombospondin-1 (THBS1) antibody - DM315 DM315-05
DM315 DM315-05 - Formalin fixed paraffin embedded human tonsil stained with Thrombospondin antibody. DM315
Thrombospondin-1 (THBS1) antibody - DM315 DM315-05
DM315 DM315-05 - Formalin fixed paraffin embedded human tonsil stained with Thrombospondin antibody. DM315

SwissProt ID

P07996 (Human), P35441 (Mouse), P35448 (Xenla), Q28178 (Bovin)

Gene ID

7057 (THBS1), 55901 (THSD1)

Available reactivities

Mam (Mammalia), Bov (Bovine), Chk (Chicken), Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), Por (Porcine), Sh (Sheep)

Available hosts

Mouse, Rabbit, Goat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Immunoprecipitation (IP), Functional assay (FN), ELISA (detection) (E(detection)), Frozen Sections (C), Immunodiffusion (ID), Enzyme Immunoassay (E)

Background of Thrombospondin-1 (THBS1) antibody

Heparin efficiently inhibits the binding of Thrombospondin to TSP. Hyaluronic acid and chondroitin sulfate show no inhibition at low concentration and only partially inhibit over the concentration range at which heparin abolishes the binding. Immunoprecipitates a 25 kDa peptide (heparinbinding domain) from chymotryptic digests of TSP that is not disulfide bonded to any other region of the TSP molecule. It inhibits the hemagglutination of trypsinized, glutaraldehyde-fixed human erythrocytes by purified TSP. Also inhibits the agglutination of fixed, activated platelets by TSP. It does not inhibit either thrombin- or A23187-induced aggregation of washed, live platelets. It does not bind to reduced and alkylated TSP or TSP transferred to nitrocellulose membrane after SDS-PAGE. It
blocks the binding of TSP to sulfatides at low concentrations. It shows no cross-reaction with fibronectin, fibrinogen, and von Willebrand factor.

General readings

1. DeFreitas MF; Yoshida CK; Frazier WA; Mendrick DL; Kypta RM; Reichardt LF. Identification of integrin alpha 3 beta 1 as a neuronal thrombospondin receptor mediating neurite outgrowth. Neuron, 1995 Aug, 15(2):333-43.
2. RayChaudhury A; Frazier WA; D'Amore PA. Comparison of normal and tumorigenic endothelial cells: differences in thrombospondin production and responses to transforming growth factor-beta. Journal of Cell Science, 1994 Jan, 107 ( Pt 1):39-46.
3. Tolsma SS; Volpert OV; Good DJ; Frazier WA; Polverini PJ; Bouck N. Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity.
Journal of Cell Biology, 1993 Jul, 122(2):497-511.
4. Frazier WA. Thrombospondins. Current Opinion in Cell Biology, 1991 Oct, 3(5):792-9.
5. Prater CA; Plotkin J; Jaye D; Frazier WA. The properdin-like type I repeats of human thrombospondin contain a cell attachment site. Journal of Cell Biology, 1991 Mar, 112(5):1031-40.
6. Good DJ; Polverini PJ; Rastinejad F; Le Beau MM; Lemons RS; Frazier WA; Bouck NP. A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proceedings of the National Academy of Sciences of the United States of America, 1990 Sep, 87(17):6624-8.
7. Frazier WA. Thrombospondin: a modular adhesive glycoprotein of platelets and nucleated cells. Journal of Cell Biology, 1987 Aug, 105(2):625-32.
8. Santoro SA; Frazier WA. Isolation and characterization of thrombospondin. Methods in Enzymology, 1987, 144:438-46.
9.Prater CA, et. al. J Cell Biol, 1991, 112(5):1031-40.

  1. Quick-Filters:
  2. Special Price (2)
  3. Highly Validated (1)
  4. Fast Delivery (2)

Items 1 to 20 of 29 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  
AP18219PU-N

Thrombospondin-1 (THBS1) (N-term) antibody

Flow cytometric analysis of MDA-MB231 cells using THBS1 Antibody (N-term) Cat.-No AP18219PU-N (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis Rabbit Hu F, ICC/IF, WB

Regular Price: 0.4 ml / €340.00

Special Price: 0.4 ml / €231.00

  Acris Antibodies GmbH
AM00242AF-N

Thrombospondin-1 (THBS1) antibody

Thrombospondin-1 (THBS1) Mouse IgM A4.1 Azide Free Bov, Chk, Hu, Ms, Rt F, FN, ICC/IF, WB
0.1 mg / €500.00
  Acris Antibodies GmbH
AM00242PU-N

Thrombospondin-1 (THBS1) antibody

Thrombospondin-1 (THBS1) Mouse IgM A4.1 Purified Bov, Chk, Hu, Ms, Rt F, ICC/IF, WB
0.1 mg / €460.00
  Acris Antibodies GmbH
AM00406AF-N

Thrombospondin-1 (THBS1) antibody

Thrombospondin-1 (THBS1) Mouse IgG1 C6.7 Azide Free Bov, Can, Eq, Hu, Por, Rt, Sh F, FN, ICC/IF, IP, WB
0.1 mg / €500.00
  Acris Antibodies GmbH
AM00406PU-N

Thrombospondin-1 (THBS1) antibody

Thrombospondin-1 (THBS1) Mouse IgG1 C6.7 Purified Bov, Can, Eq, Hu, Por, Rt, Sh F, ICC/IF, IP, WB
0.1 mg / €460.00
  Acris Antibodies GmbH
AM00631PU-N

Thrombospondin-1 (THBS1) antibody

Thrombospondin-1 (THBS1) Mouse IgG1 D4.6 Purified Bov, Can, Eq, Hu, Ms, Por, Rt, Sh IP, WB
0.1 mg / €460.00
  Acris Antibodies GmbH
AP18219CP-N

Thrombospondin-1 (THBS1) Control Peptide

Thrombospondin-1 (THBS1)
0.1 mg / €120.00
  Acris Antibodies GmbH
AP23121PU-N

Thrombospondin-1 (THBS1) (N-term) antibody

Formalin-Fixed, Paraffin-Embedded Human Placenta stained with Thrombospondin-1 Antibody Cat.-No AP23121PU-N at 3.75 µg/ml after heat-induced antigen retrieval. Goat Purified Hu P
50 µg / €380.00
  Acris Antibodies GmbH
AP33064SU-N

Thrombospondin-1 (THBS1) antibody

Thrombospondin-1 (THBS1) Rabbit Serum Hu ID, IP
1 ml / €390.00
  Acris Antibodies GmbH
AP33184PU-N

Thrombospondin-1 (THBS1) antibody

HEK293 lysate (10 µg protein in RIPA buffer) overexpressing Human THBS1 with C-terminal MYC tag probed with AP33184PU-N (1 µg/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with AP33184PU-N (1ug/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €270.00
  Acris Antibodies GmbH
AP33185PU-N

Thrombospondin-1 (THBS1) (N-term) antibody

HEK293 lysate (10 µg protein in RIPA buffer) overexpressing Human THBS1 with C-terminal MYC tag probed with AP33185PU-N (0.1 µg/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with AP33185PU-N (0.1 µg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €270.00
  Acris Antibodies GmbH
DM315

Thrombospondin-1 (THBS1) antibody

Formalin fixed paraffin embedded human tonsil stained with Thrombospondin antibody. DM315 Mouse IgG1 A6.1 Purified Mam ICC/IF, P, WB
1 ml / €540.00
  Acris Antibodies GmbH
DM315-05

Thrombospondin-1 (THBS1) antibody

Formalin fixed paraffin embedded human tonsil stained with Thrombospondin antibody. DM315 Mouse IgG1 A6.1 Purified Mam ICC/IF, P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH
NB600-554

Thrombospondin-1 (THBS1) antibody

Western Blot: Thrombospondin Antibody (A4.1) [NB600-554] - Western Blot of TSP from Human Cells in a Non-reducing Gel. Mouse IgM A4.1 Purified Bov, Chk, Hu, Ms, Rt F, ICC/IF, WB
0.5 ml / €370.00
  Novus Biologicals Inc.
NBP1-39864

Thrombospondin-1 (THBS1) antibody

Thrombospondin-1 (THBS1) Mouse IgG1 Bov, Hu, Ms, Por, Rt C, F, ICC/IF, IP, WB
50 µg / €430.00
  Novus Biologicals Inc.
NBP1-52410

Thrombospondin-1 (THBS1) antibody

Thrombospondin-1 (THBS1) Goat Aff - Purified Hu, Ms, Rt P
50 µg / €430.00
  Novus Biologicals Inc.
GTX100746

Thrombospondin-1 (THBS1) antibody

Thrombospondin-1 (THBS1) Rabbit Aff - Purified Hu WB
0.1 ml / €220.00
  GeneTex Inc.
H00007057-B01P

Thrombospondin-1 (THBS1) antibody

Western Blot analysis of THBS1 expression in transfected 293T cell line (H00007057-T01) by THBS1 MaxPab polyclonal antibody.

Lane 1: THBS1 transfected lysate(128.7 KDa).
Lane 2: Non-transfected lysate.
Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €340.00
  Abnova Taiwan Corp.
bs-2715R

Thrombospondin-1 (THBS1) antibody

Formalin-fixed and paraffin embedded human placenta labeled with Anti-TSP-1/THBS1 Polyclonal Antibody, Unconjugated (bs-2715R) at 1:200, followed by conjugation to the secondary antibody and DAB staining Rabbit IgG Aff - Purified Bov, Chk, Hu, Ms, Por, Rt E, ICC/IF, P
0.1 ml / €220.00
  Bioss, Inc.

Proteins, Peptides & Growth Factors

Catalog No. Species Pres. Purity Source  
BA675

Thrombospondin-1 (THBS1)

Thrombospondin-1 (THBS1) Human Purified > 95 % > 95% (SDS-PAGE) Platelets

Regular Price: 25 µg / €260.00

Special Price: 25 µg / €168.00

  Acris Antibodies GmbH

Items 1 to 20 of 29 total

per page
Page:
  1. 1
  2. 2
  • Pinterest
  • LinkedIn