discontinued

GTX14114 14-3-3 protein beta+zeta antibody

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50 µg / €350.00

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Mouse anti Bovine, Canine, Human, Monkey, Mouse, Porcine, Rat, Sheep 14-3-3 protein beta+zeta 4E2

GTX14114

Product Description for 14-3-3 protein beta+zeta

Mouse anti Bovine, Canine, Human, Monkey, Mouse, Porcine, Rat, Sheep 14-3-3 protein beta+zeta 4E2.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for 14-3-3 protein beta+zeta

Product Category Primary Antibodies
Quantity 50 µg
Synonyms KCIP-1, Protein Kinase C Inhibitor Protein 1, YWHAB, YWHAZ
Presentation Purified
Reactivity Bov, Can, Hu, Mky, Ms, Por, Rt, Sh
Applications ICC/IF, WB
Clonality Monoclonal
Clone 4E2
Host Mouse
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Tissue / cell preparation (Lysed transformed human amnion cells).
Application ICC, WB
Background 14-3-3 proteins are highly conserved proteins which play a role in both signal transduction and progression through the cell cycle by binding to and regulating several different proteins. 14-3-3 proteins activate tyrosine and tryptophan hydroxylases and protein kinase C. They mediate signal transduction by binding to phosphoserine-containing proteins. There are at least 7 mammalian isoforms: alpha, beta, gamma, delta, epsilon, zeta, and eta. An eighth subtype, termed theta has been found in rat brain. The 14-3-3 proteins exists in vitro and in vivo as either homo- or heterodimers which interact via their N-terminal domains and are subject to phosphorylation by protein kinase C. 14-3-3 proteins are localized in the cytoplasm of neurons in the cerebral cortex and are axonally transported to the nerve terminals. They may be present at lower levels in various other eukaryotic tissues. Northern blot analysis has shown expression of the eta chain in cultured cell lines derived from various tumors.
Format
Purification:
Protein G purified
Buffer System:
Preservative: NoneConstituents: 50% Glycerol, 10mM PBS, 0.1mM PMSF. pH 7.2
Purity:
Protein G purified
State:
Purified
Specificity
Specificity:
Cross-reacts with Human, Mouse, Rat, Cow, Dog, Monkey, Pig and Sheep. Not yet tested in other species.

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