discontinued

AM20768PU-N 2-Cys-Peroxiredoxin antibody

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0.1 mg / €470.00

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Mouse anti Human, Mouse 2-Cys-Peroxiredoxin 6E5

AM20768PU-N

Product Description for 2-Cys-Peroxiredoxin

Mouse anti Human, Mouse 2-Cys-Peroxiredoxin 6E5.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for 2-Cys-Peroxiredoxin

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms 2 Cys Peroxiredoxin, Redox enzyme
Presentation Purified
Reactivity Hu, Ms
Applications E, WB
Clonality Monoclonal
Clone 6E5
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Recombinant Human protein purified from E.coli
Application ELISA.
Western Blot (1/1000)
Positive Control: HeLa cells.
Background Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis.
Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kDa in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol (1).
General Readings
  1. Wood, Z. A. et al. (2003) Trends Biochem Sci. 28(1):32-40.
Storage Store the antibody (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Format
Purification:
Ammonium Sulfate Precipitation
Buffer System:
HEPES with 0.15M NaCl, 0.01% BSA, 0.03% Sodium Azide and 50% Glycerol
State:
Liquid purified IgG fraction
Purified
Specificity
Specificity:
Recognizes 2-Cys-Peroxiredoxin.
Species:
Human and Mouse.

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