GTX41165 26S Proteasome antibody

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5 ml / €520.00

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Mouse anti Human, Xenopus 26S Proteasome p32(26S-161)


Product Description for 26S Proteasome

Mouse anti Human, Xenopus 26S Proteasome p32(26S-161).
Product is tested for Frozen Sections, Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for 26S Proteasome

Product Category Primary Antibodies
Quantity 5 ml
Reactivity Hu, Xen
Applications C, E, ICC/IF, WB
Clonality Monoclonal
Clone p32(26S-161)
Host Mouse
Isotype IgG1
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

26S complexes of Xenopus laevis oocytes.
Application ELISA, IF, IHC-F, IHC-Fr, WB
Background The 26S proteasome is an ATP-dependent, multisubunit (~31), barrel-shaped molecular machine with an apparent molecular weight of ~2.5 MDa. It consists of a 20S proteolytic core complex which is crowned at one or both ends by 19S regulatory subunit complexes. The 19S regulatory subunits recognize ubiquitinated proteins and play an essential role in unfolding and translocating targets into the lumen of the 20S subunit. An enzymatic cascade is responsible for the attachment of multiple ubiquitin molecules to lysine residues of proteins targeted for degradation. Several genetic diseases are associated with defects in the ubiquitin-proteasome pathway. Some examples of affected proteins include those linked to cystic fibrosis, Angelman's syndrome, and Liddle syndrome.
Storage Keep as concentrated solution, aliquot and store at 4
Cell Culture
Buffer System:
Preservative: 0.09% Sodium Azide
Cell Culture
Cross-reacts with Human and Xenopus laevis and cell lines XLKE-A6 (Xenopus), PLC (human), and Ptk2 (rat kangaroo). Not yet tested in other species.

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