bs-9450R 5-Methylcytosine / 5-MeC antibody

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Rabbit anti 5-Methylcytosine / 5-MeC

Product Description for 5-Methylcytosine / 5-MeC

Rabbit anti 5-Methylcytosine / 5-MeC.
Presentation: Purified
Product is tested for Paraffin Sections.

Properties for 5-Methylcytosine / 5-MeC

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms 5-MeCyd, 5-Methyl Cytidine, 5-Methyl Cytosin, 5-Methylcytidine, 5MeC
Presentation Purified
Applications P
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

KLH conjugated 5 MethylCytosine.
Background Cytidine is a nucleoside formed by a cytosine attached to a ribose ring via a beta-N1-glycosidic bond. DNA is methylated on cytidines by DNA methylases (DNMTs)to generate 5-methylcytidine (5-mC), a potent epigenetics marker and regulator of gene expression. The reverse reaction (cytidine demethylation) starts with its oxidation to hydroxymethyl- (5-hmC), formyl- (5-fC), and carboxy- (5-caC) cytidine. Several enzymes, including the Tet family of proteins have been implicated in cytidine demethylation.
Storage Store at -20°C for 12 months.
Purified by Protein A and peptide affinity chromatography.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.

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