bs-1278R 8-Hydroxy-Guanosine / 8-OHG antibody

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Rabbit anti 8-Hydroxy-Guanosine / 8-OHG


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  • bs-1278R

Product Description for 8-Hydroxy-Guanosine / 8-OHG

Rabbit anti 8-Hydroxy-Guanosine / 8-OHG.
Presentation: Purified
Product is tested for Paraffin Sections.

Properties for 8-Hydroxy-Guanosine / 8-OHG

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms 8-Hydroxy-2'-deoxyguanosine, 8-Hydroxyguanine, 8-Hydroxyguanosine, 8-OFdG, 8-OHG, 8OG, 8OHG, 8OHdG
Presentation Purified
Applications P
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

KLH conjugated 8-OhdG.
Background 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.
Product Citations
Originator or purchased from resellers:
  1. Zhang, Ting-Ting, et al. "Electrochemiluminescence immunosensor for highly sensitive detection of 8-hydroxy-2′-deoxyguanosine based on carbon quantum DoT coated Au/SiO2 core-shell nanoparticles." Talanta (2014).
  2. Yong, Rachel, et al. "Plumbagin Ameliorates Diabetic Nephropathy via Interruption of Pathways that Include NOX4 Signalling." PLOS ONE 8.8 (2013): e73428.
Storage Store at -20°C for 12 months.
Purified by Protein A and peptide affinity chromatography.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.

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