AP20818PU-N ABL1 / ABL2 pTyr393/439 antibody

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0.1 mg / €350.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat ABL1 / ABL2

AP20818PU-N

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  • AP20818PU-N

Product Description for ABL1 / ABL2

Rabbit anti Human, Mouse, Rat ABL1 / ABL2.
Properties: pTyr393/439
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Properties for ABL1 / ABL2

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms ABL1, ABL2, Abelson murine leukemia viral oncogene homolog 1, JTK7, Proto-oncogene tyrosine-protein kinase ABL1, bcr/abl, c-ABL, p150
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications ICC/IF, P, WB
Clonality Polyclonal
Host Rabbit
Molecular weight ~ 123 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P00519
Immunogen:
Synthetic phosphopeptide derived from human ABL1/2 around the phosphorylation site of Tyrosine 393/439.
GeneID:
25
Property pTyr393/439
Application Western blot: 1/500-1/1000.
Immunofluorescence: 1/50-1/200.
Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Background The Abl oncogene was initially identified as the viral transforming gene of Abelson murine leukemia virus (A-MuLV). The major translational product of c-Abl has been identified as a protein with tyrosine kinase activity and an SH2 domain. The Abl oncogene is implicated in several human leukemias including 90-95% of chronic myelocytic leukemia (CML), 20-25% of adult acute lymphoblastic leukemia (ALL) and 2-5% of pediatric ALL. In these leukemias the c-Abl protooncogene undergoes a (9;22) chromosomal translocation producing the Philadelphia (Ph1) chromosome. The molecular consequence of this translocation is the generation of a chimeric Bcr/c-Abl mRNA encoding activated Abl proteintyrosine kinase. The Bcr gene has been shown to encode a GTPase-activating protein (GAP) specific for the Ras-related GTP-binding protein, p21rac.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography using epitope-specific immunogen.
Buffer System:
Phosphate buffered saline (PBS), pH~7.2
Preservatives:
0.05% Sodium Azide
State:
Liquid purified Ig fraction (> 95% (by SDS-PAGE).
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Mouse, Rat.
Specificity
Specificity:
This antibody detects endogenous levels of ABL1/2 protein when phosphorylated at Tyr393/439.
Gene ID 25

Accessory Products

Proteins and/or Positive Controls

Proteins for ABL1 / ABL2 (17 products)

Catalog No. Species Pres. Purity   Source  

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

ABL1

ABL1 Human
  Abnova Taiwan Corp.

Positive controls for ABL1 / ABL2 (2 products)

Catalog No. Species Pres. Purity   Source  

c Abl Lysate

Western Blot: c Abl Lysate [NBL1-07208] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for ABL1 Protein
  Novus Biologicals Inc.

c Abl Lysate

Western Blot: c Abl Lysate [NBL1-07209] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for ABL1 Protein
  Novus Biologicals Inc.
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