BB-MA1000 Actin antibody

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0.1 mg / €290.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Chicken, Human, Mouse, Rat Actin AC-40


Product Description for Actin

Mouse anti Chicken, Human, Mouse, Rat Actin AC-40.
Presentation: Ascites
Product is tested for Immunocytochemistry/Immunofluorescence, Frozen Sections, Western blot / Immunoblot.

Properties for Actin

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Ascites
Reactivity Chk, Hu, Ms, Rt
Applications C, ICC/IF, WB
Clonality Monoclonal
Clone AC-40
Host Mouse
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Boster Immunoleader
Manufacturer certificates ISO 9001

Datasheet Extract

Synthetic actin C-terminal peptideSer-Gly-Pro-Ser-Ile-Val-His-Arg-Lys-Cys-Phe,attached to a Multiple Antigen Peptide (MAP) backbone.
Background Actin, a highly conserved protein, is a major component of both the cytoskeletal and contractile structures in the cell types. It varies in amount, being related to the type of differentiation and to the functional state of cells and tissues. The actins exhibit over 90% sequence homology, but each isoform has a unique NH2-terminal sequence. The isoforms are comprised of three alpha-actin, one beta-actin, two gamma-actin. Because the amino acid sequence of the C-terminal is the same for almost all actins, this antibody has been raised using a synthetic peptide corresponding to the C-terminal 11 residues.
General Readings
  1. Gunning P, Ponte P, Okayama H, Engel J, Blau H, Kedes L. Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed. Mol Cell Biol. 1983 May;3(5):787-95. PubMed PMID: 6865942. (Free PMC Article available)
  2. Goebel HH, Brockmann K, Bönnemann CG, Warlo IA, Hanefeld F, Labeit S, et al. Actin-related myopathy without any missense mutation in the ACTA1 gene. J Child Neurol. 2004 Feb;19(2):149-53. PubMed PMID: 15072110.
  3. Laing NG, Clarke NF, Dye DE, Liyanage K, Walker KR, Kobayashi Y, et al. Actin mutations are one cause of congenital fibre type disproportion. Ann Neurol. 2004 Nov;56(5):689-94. PubMed PMID: 15468086.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

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