AM26130PU-N Activated Macrophages antibody

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0.1 mg / €420.00
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Quick Overview

Rat anti Mouse Activated Macrophages 88a

Product Description for Activated Macrophages

Rat anti Mouse Activated Macrophages 88a.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Flow Cytometry.

Properties for Activated Macrophages

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Ms
Applications C, F
Clonality Monoclonal
Clone 88a
Host Rat
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Supernatant of stimulated lymphocytes
Add. information Antigen distribution:
Isolated cells: The antigen is found on granulocytes, monocytes and bone marrow cells.
Tissue sections: The 88a antigen is found on dendritic cells in T- and B-cell areas as well as on marginal zone macrophages in lymphoid tissues. Typical macrophages in other organs show less or no expression of the 88a antigen.
Application Immunohistochemistry on frozen sections: 2 μg/ml (1:100).
Has been described to work in FACS.
Suggested positive control: Mouse spleen.
Background The antigen is a 200kD (glyco-)protein with unknown function. The antigen is expressed at low levels by bone marrow monocytes and granulocytes, and increases upon maturation in vitro. The expression is also enhanced after MIF treatment of macrophages. The antigen is displayed by both immature and mature Kupffer cells.
General Readings
  1. Michels E. et al.: Phenotypic alterations induced in macrophages by migration inhibitory factors. In: Cellular and Molecular Biology of Lymphokines (C. Sorg & A. Schimpel, ed.), p 321-25 (1985).
  2. Freudenberg N, Piotraschke J, Galanos C, Sorg C, Askaryar FA, Klosa B, et al. The role of macrophages in the uptake of endotoxin by the mouse liver. Virchows Arch B Cell Pathol Incl Mol Pathol. 1992;61(5):343-9. PubMed PMID: 1348896.
Storage Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Affinity chromatography
Buffer System:
Stock solution contains 0.2mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 10mg/ml bovine serum albumin (BSA) as a stabilizer and 0.01% thimerosal as a preservative.
Lyophilized Ig fraction
Aff - Purified
Reconstitute by adding 0.5ml distilled water.
Species Reactivity
Species reactivity (tested):
This antibody detects Macrophages, dendritic cells, granulocytes.

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