discontinued

NBP1-59708 Activin Receptor Type IIB antibody

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50 µg / €440.00

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Rabbit anti Canine, Human Activin Receptor Type IIB

Product Description for Activin Receptor Type IIB

Rabbit anti Canine, Human Activin Receptor Type IIB.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for Activin Receptor Type IIB

Product Category Primary Antibodies
Quantity 50 µg
Presentation Aff - Purified
Reactivity Can, Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q4VAU9
Immunogen:
Synthetic peptides corresponding to ACVR2B(activin A receptor, type IIB) The peptide sequence was selected from the C terminal of ACVR2B. Peptide sequence HDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI.
Background Activin receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. ACVR2B is activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
Storage Store at -20C. Avoid freeze-thaw cycles.
Format
Purification:
Peptide affinity purified
Buffer System:
This product is lyophilized and contains PBS and 2% Sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml.
State:
Aff - Purified

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