bs-5849R ADAM18 antibody

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Rabbit anti Human ADAM18


Product Description for ADAM18

Rabbit anti Human ADAM18.
Presentation: Purified
Product is tested for Flow Cytometry, Paraffin Sections, Western blot / Immunoblot.

Properties for ADAM18

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms A disintegrin and metalloproteinase domain 18, ADA18_HUMAN, ADAM 18, ADAM 27, ADAM metallopeptidase domain 18, ADAM27, MGC41836, MGC88272, TMDC3, Transmembrane metalloproteinase like, and cysteine rich protein III., disintegrin like, tMDCIII
Presentation Purified
Reactivity Hu
Applications F, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

Swiss Prot Num:
KLH conjugated synthetic peptide derived from human ADAM18.
Application WB(1:100-1000)
Background ADAM18 was first described as tMDC III (testis-specific Metalloproteinase-like disintergin-like cysteine-rich protein-III). ADAM18 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the fill-length ADAM18 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a short spacer region, then the transmembrane domain and a cytoplasmic domain. Like many of the reproductive-specific ADAMS, ADAM18 plays a nonenzymatic role, or (as is the case for ADAMs 1 & 2 (fertilin alpha and beta)), the protein acts in concert with a proteolytically active ADAM to process proteins. Little is known about interactions between ADAM18 and other ADAMs. To date, 4 different sequences for human ADAM18 are published; 739, 715, 182 and 153 amino acids in length.
Storage Store at -20°C for 12 months.
Purified by Protein A.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.

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