AM32478SU-N Adeno-Associated Virus 8 / AAV8 (intact particle) antibody

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5 ml / €300.00
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Mouse anti Adeno-Associated Virus 8 / AAV8 ADK8


Product Description for Adeno-Associated Virus 8 / AAV8

Mouse anti Adeno-Associated Virus 8 / AAV8 ADK8.
Properties: (intact particle)
Presentation: Supernatant
Product is tested for Immunoprecipitation, Neutralisation, Immunocytochemistry/Immunofluorescence, Frozen Sections, Dot blot, Enzyme Immunoassay.

Properties for Adeno-Associated Virus 8 / AAV8

Product Category Primary Antibodies
Quantity 5 ml
Synonyms AAV-8
Presentation Supernatant
Applications C, Dot, E, ICC/IF, IP, NEUT
Clonality Monoclonal
Clone ADK8
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Recombinantly produced adeno-associated virus type 8 (AAV-8) vector, carrying GFP
Property intact particle
Application ELISA. 
Neutralization Studies.

Immunofluorescence Microscopy.
Immunohistochemistry: Ready-to-use.
Dot Blot (non-denaturing conditions).
Incubation Time: Overnight at 2-8°C for use in Immunohistochemistry or Immunofluorescence Microscopy. 
Not Suitable for Immunoblotting using denaturing conditions.
General Readings
  1. Sonntag F, Köther K, Schmidt K, Weghofer M, Raupp C, Nieto K, et al. The assembly-activating protein promotes capsid assembly of different adeno-associated virus serotypes. J Virol. 2011 Dec;85(23):12686-97. doi: 10.1128/JVI.05359-11. Epub 2011 Sep 14. PubMed PMID: 21917944. (Free PMC Article available, 10 images available)
  2. Gurda BL, Raupp C, Popa-Wagner R, Naumer M, Olson NH, Ng R, et al. Mapping a neutralizing epitope onto the capsid of adeno-associated virus serotype 8. J Virol. 2012 Aug;86(15):7739-51. doi: 10.1128/JVI.00218-12. Epub 2012 May 16. PubMed PMID: 22593150. (Free PMC Article available, 8 images available)
  3. Mietzsch M, Grasse S, Zurawski C, Weger S, Bennett A, Agbandje-McKenna M, et al. OneBac: platform for scalable and high-titer production of adeno-associated virus serotype 1-12 vectors for gene therapy. Hum Gene Ther. 2014 Mar;25(3):212-22. doi: 10.1089/hum.2013.184. Epub 2014 Jan 23. PubMed PMID: 24299301. (Free PMC Article available)
Storage Store undiluted at 2-8°C.
Shelf life: one year from despatch.
0.09% Sodium Azide
Liquid Culture Supernatant
Species Reactivity
Species reactivity (tested):
AAV-8, found in Monkey.
For characterization of different stages of infection Specificity and very useful for the analysis of the AAV assembly process.
ADK8 specifically reacts with intact adeno-associated virus particles, empty and full capsids. Recognizes a conformational epitope of assembled capsids.
Predicted binding site: Residues 586-LQQQNT-591 (cf. Gurda et al.).
No cross-reaction with other AAV types in Immunofluorescence microscopy. 
With Dot Blot analysis weak cross-reactivity with type 1, 3, 7 and 10 was observed (Mietzsch et al. 2013).

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