AP05003PU-N Adenovirus E1A (E1A) antibody

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0.1 mg / €360.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Sheep anti Adenovirus E1A

Product Description for Adenovirus E1A

Sheep anti Adenovirus E1A.
Properties: (E1A)
Presentation: Purified
Product is tested for Immunoprecipitation.

Properties for Adenovirus E1A

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Adenovirus early region 1 antibody, Control protein E1A antibody, E1A antibody
Presentation Purified
Applications IP
Clonality Polyclonal
Host Sheep
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
GST-EIA fusion protein recognizing a 43kD protein.
Property E1A
Application Western Blot: 1-10 µg /ml.
Positive Control: 293 cells are human embryonic kidney cells that have been transformed with the adenovirus genes E1A and E1B, which are required for adenovirus propagation. This cell line can be used as a positive control for this antibody.
Background The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.
EIA gene encodes potent onco-proteins that modify the normal transcriptional growth regulation of key cellular genes and thus alter cell cycle control.
Concentration Lot specific
Storage Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Buffer System:
Phosphate buffered saline with 0.08% Sodium Azide
Purity:
Purified
State:
Liquid purified Ig (0.2µm sterile filtered)
Purified
Specificity
Specificity:
This antibody reacts to Adenovirus E1A.

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