bs-1158R AGE antibody

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Rabbit anti Human, Mouse, Rat AGE

Product Description for AGE

Rabbit anti Human, Mouse, Rat AGE.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for AGE

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms Advanced Glycation End Products
Presentation Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

Background Advanced Glycation End products (AGEs) are the result of a chain of chemical reactions after an initial glycation reaction. The intermediate products are known, variously, as Amadori, Schiff base and Maillard products, named after the researchers who first described them. (The literature is inconsistent in applying these terms. For example, Maillard reaction products are sometimes considered intermediates and sometimes end products.) Side products generated in intermediate steps may be oxidizing agents (such as hydrogen peroxide), or not (such as beta amyloid proteins).[1] "Glycosylation" is sometimes used for "glycation" in the literature, usually as 'non-enzymatic glycosylation. The AGE modified BSA was produced by reacting BSA with glycolaldehyde under sterile conditions followed by extensive dialysis and purification steps.
Product Citations
Originator or purchased from resellers:
  1. Lu, Lin, et al. "Effects of atorvastatin on progression of diabetic nephropathy and local RAGE and soluble RAGE expressions in rats." Journal of Zhejiang University SCIENCE B 12.8 (2011): 652-659.
  2. Ye, Ruidong, et al. "Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats." Neurochemistry international 58.3 (2011): 391-398.
  3. Huang, Kaipeng, et al. "Sirt1 resists AGEs-induced expressions of FN and TGF-β1 by activating the Nrf2/ARE pathway in GMCs." Free Radical Biology and Medicine (2013).
Storage Store at -20°C for 12 months.
Purified by Protein A and peptide affinity chromatography.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.

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