AP26397PU-N AGGF1 / VG5Q antibody

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0.1 mg / €440.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human AGGF1 / VG5Q

AP26397PU-N

Product Description for AGGF1 / VG5Q

Rabbit anti Human AGGF1 / VG5Q.
Presentation: Purified
Product is tested for Western blot / Immunoblot, Immunoprecipitation, Enzyme Immunoassay, Paraffin Sections, Frozen Sections.

Properties for AGGF1 / VG5Q

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Angiogenic factor VG5Q, Angiogenic factor with G patch and FHA domains 1, G patch domain-containing protein 7, GPATC7, GPATCH7, Vasculogenesis gene on 5q protein
Presentation Purified
Reactivity Hu
Applications C, E, IP, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q8N302
Immunogen:
VG5Q functions as an angiogenic factor in promoting angiogenesis and suppression of VG5Q expression inhibits vessel formation. Angiogenic factors are critical to the initiation of angiogenesis and maintenance of the vascular network. Angiogenesis has an essential role in pathological conditions such as cancer and various ischaemic and inflammatory diseases.
VG5Q can bind to endothelial cells and promote cell proliferation, suggesting that the protein may act in an autocrine fashion. VG5Q interacts with TWEAK (also known as TNFSF12), another secreted angiogenic factor.
VG5Q shows strong expression in blood vessels and is secreted when vessel formation is initiated. VG5Q protein was detected mostly in the cytoplasm and around the nuclei of human microvascular endothelial cells (HMVECs). Furthermore VG5Q is detected in human umbilical vein endothelial cells (HUVECs), human heart fibroblast (HHF) and ovarian cancer cells (OV-3), but low expression was detected in kidney cancer cells (RP-45), HeLa Cells and bladder cancer cells.
GeneID:
55109
Application Immunohistochemistry on frozen sections.
Immunohistochemistry on paraffin sections.
Immunoassays.
Immunoprecipitation.
Western blot.
Concentration 0.1 mg/ml
General Readings
  1. Tian XL, Kadaba R, You SA, Liu M, Timur AA, Yang L, et al. Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome. Nature. 2004 Feb 12;427(6975):640-5. PubMed PMID: 14961121. (Free PMC Article available, 4 images available)
Storage

Store at 2 - 8 °C.
Shelf life: one year from despatch.

Format
Purification:
Protein A
Buffer System:
PBS
Preservatives:
0.02% sodium azide
Stabilizers:
0.1% bovine serum albumin
State:
Liquid 0.2 µm filtered Ig fraction
Purified
Species Reactivity
Species reactivity (tested):
Human
Specificity
Specificity:
The antibody reacts with human VG5Q, a 84 kDa protein.
Gene ID 55109

Accessory Products

Proteins and/or Positive Controls

Proteins for AGGF1 / VG5Q (2 products)

Catalog No. Species Pres. Purity   Source  

AGGF1 / VG5Q

AGGF1 / VG5Q Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

AGGF1 / VG5Q

AGGF1 / VG5Q Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for AGGF1 / VG5Q (2 products)

Catalog No. Species Pres. Purity   Source  

AGGF1 293T Cell Transient Overexpression Lysate(Denatured)

AGGF1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

VG5Q 293T Cell Transient Overexpression Lysate(Denatured)

VG5Q 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.
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