AM26017PU-N AGR3 antibody

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0.1 mg / €310.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Mouse anti Human AGR3 AGR3.1

AM26017PU-N

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  • AM26017PU-N

Product Description for AGR3

Mouse anti Human AGR3 AGR3.1.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Frozen Sections, Paraffin Sections, Western blot / Immunoblot, Flow Cytometry.

Properties for AGR3

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Anterior gradient protein 3 homolog, BCMP11, HAG-3, HAG3, breast cancer membrane protein 11
Presentation Aff - Purified
Reactivity Hu
Applications C, F, ICC/IF, P, WB
Clonality Monoclonal
Clone AGR3.1
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q8TD06
Immunogen:
Purified Human AGR3 protein.
GeneID:
155465
Application Western blot: 1 μg/ml.
Positive Control: T47D breast cancer cell line.
Negative Control: H1299 lung carcinoma cell line.
Immunohistochemistry on Paraffin Sections: 1 μg/ml.
Positive Tissue: breast cancer.
Immunohistochemistry on Frozen Sections: 1 μg/ml.
Positive Tissue: breast cancer.
Immunocytochemistry: 1 μg/ml.
Positive Control: T47D breast cancer cell line.
Negative Control: H1299 lung carcinoma cell line.
Background AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.
Concentration 1.0 mg/ml
General Readings
  1. Persson S, Rosenquist M, Knoblach B, Khosravi-Far R, Sommarin M, Michalak M. Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family. Mol Phylogenet Evol. 2005 Sep;36(3):734-40. PubMed PMID: 15935701.
  2. Fletcher GC, Patel S, Tyson K, Adam PJ, Schenker M, Loader JA, et al. hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan. Br J Cancer. 2003 Feb 24;88(4):579-85. PubMed PMID: 12592373. (Free PMC Article available, 4 images available)
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography on Protein A
Buffer System:
PBS
Preservatives:
15 mM Sodium Azide
Stabilizers:
0.2% (w/v) high-grade protease free BSA
State:
Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Aff - Purified
Specificity
Specificity:
This antibody recognizes the epitope HETTDKNLS within the AGR3 (AG3) protein (19-20 kDa), a secreted cytoplasmic protein which can serve as a marker of carcinogenesis.
Species:
Human.
Gene ID 155465

Accessory Products

Proteins and/or Positive Controls

Proteins for AGR3 (6 products)

Catalog No. Species Pres. Purity   Source  

AGR3

AGR3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

AGR3

AGR3 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €299.00
  OriGene Technologies, Inc.

AGR3 (22-166, His-tag)

AGR3 Human Purified > 90 % E. coli
0.5 mg / €750.00
  OriGene Technologies GmbH

AGR3 (22-166, His-tag)

AGR3 Human Purified > 90 % E. coli
0.1 mg / €300.00
  OriGene Technologies GmbH

AGR3

AGR3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

AGR3

AGR3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Positive controls for AGR3 (2 products)

Catalog No. Species Pres. Purity   Source  

AGR3 Lysate

Western Blot: AGR3 Lysate [NBL1-07390] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for AGR3 Protein
  Novus Biologicals Inc.

AGR3 overexpression lysate

AGR3 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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