TA505453 Alpha-crystallin A chain / CRYA1 antibody

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0.1 ml / €379.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti Human Alpha-crystallin A chain / CRYA1 OTIC3

TA505453

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Product Description for Alpha-crystallin A chain / CRYA1

Mouse anti Human Alpha-crystallin A chain / CRYA1 OTIC3.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for Alpha-crystallin A chain / CRYA1

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms CRYAA, HSPB4, Heat shock protein beta-4
Presentation Purified
Reactivity Hu
Applications P, WB
Clonality Monoclonal
Clone OTIC3
Host Mouse
Isotype IgG2b
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P02489
Immunogen:
Full length human recombinant protein of human CRYAA(NP_000385) produced in HEK293T cell.
GeneID:
102724652
Isotype control AM03110PU-N, SM12P
Application WB 1:2000
IHC 1:150
Background Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-termil extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not reture proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translatiol modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additiol functions of alpha crystallins are an autokise activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Defects in this gene cause autosomal domint congenital cataract (ADCC). [provided by RefSeq, Jul 2008].
Format
Purification:
Purified from mouse ascites fluids by affinity chromatography
Buffer System:
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for Alpha-crystallin A chain / CRYA1 (6 products)

Catalog No. Species Pres. Purity   Source  

Alpha-crystallin A chain / CRYA1

Alpha-crystallin A chain / CRYA1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Alpha-crystallin A chain / CRYA1

Recombinant human CRYAA: 14% SDS-PAGE Human Purified ≥ 95 by SDS-PAGE E. coli
0.1 mg / €230.00
  Acris Antibodies GmbH

Alpha-crystallin A chain / CRYA1

Recombinant human CRYAA: 14% SDS-PAGE Human Purified > 95 % by SDS-PAGE E. coli
1 mg / €590.00
  Acris Antibodies GmbH

Alpha-crystallin A chain / CRYA1

Alpha-crystallin A chain / CRYA1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Alpha-crystallin A chain / CRYA1

Alpha-crystallin A chain / CRYA1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Alpha-crystallin A chain / CRYA1

SDS-Page: alpha A Crystallin Protein [NBC1-18351] - Crystallin alpha A, 19.9kDa (173aa) with a purity of 95% by SDS - PAGE Protein
0.1 mg / €310.00
  Novus Biologicals Inc.

Positive controls for Alpha-crystallin A chain / CRYA1 (1 products)

Catalog No. Species Pres. Purity   Source  

CRYAA overexpression lysate

CRYAA overexpression lysate
0.1 mg / €280.00
  OriGene Technologies, Inc.
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