AM32632PU-N Amyloid beta (N-term) antibody

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0.5 mg / €430.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human Amyloid beta NT 1H3

Product Description for Amyloid beta

Mouse anti Human Amyloid beta NT 1H3.
Properties: (N-term)
Presentation: Aff - Purified
Product is tested for Frozen Sections.

Properties for Amyloid beta

Product Category Primary Antibodies
Quantity 0.5 mg
Synonyms ABPP, APPI, Alzheimer disease amyloid protein, Amyloid Precursor Protein, CVAP, Cerebral vascular amyloid peptide, PreA4, Protease nexin-II
Presentation Aff - Purified
Reactivity Hu
Applications C
Clonality Monoclonal
Clone NT 1H3
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Full length Human beta amyloid peptide 43.
Property N-term
Application Immunohistochemistry.
Background Amyloid beta precursor protein gene (ABPP) encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Multiple transcript variants encoding several different isoforms have been found for this gene. Isoform APP695 is the predominant form in neuronal tissue, isoform APP751 and isoform APP770 are widely expressed in nonneuronal cells. Isoform APP751 is the most abundant form in T lymphocytes. ABPP is expressed in all fetal tissues examined with the highest levels in brain, kidney, heart and spleen with weak expression observed in liver; ABPP is induced during neuronal differentiation. In the adult brain, highest expression of ABPP gene is found in the frontal lobe of the cortex and in the anterior perisylvian cortex opercular gyri; moderate expression in the cerebellar cortex, the posterior perisylvian cortex opercular gyri and the temporal associated cortex. Weak expression is found in the striate, extra striate and motor cortices. Mutations in ABPP have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
Storage

Store (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Affinity Chromatography on Protein G
Buffer System:
0.01M PBS, pH7.2
State:
Lyophilized purified IgG fraction
Aff - Purified
Reconstitution:
Restore in double distillated water is recommended to adjust the final concentration to 1.0 mg/ml.
Specificity
Specificity:
This antibody recognizes the N-terminal sequence of Human beta Amyloid peptides.
Species:
Human.

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