GTX10602 Angiopoietin 3 [113504] antibody

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0.1 mg / €290.00

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Rat anti Mouse Angiopoietin 3 [113504] 113504


Product Description for Angiopoietin 3 [113504]

Rat anti Mouse Angiopoietin 3 [113504] 113504.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Angiopoietin 3 [113504]

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Ms
Applications E, WB
Clonality Monoclonal
Clone 113504
Host Rat
Isotype IgG2b
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Recombinant full length protein (Mouse).
Application ELISA, WB
Background Angiopoietin 3 (ANG3), also called ANG4, might represent counterparts in mouse and human. Based on chromosomal analysis, mouse ANG3 is thought to be an ortholog of human ANG4. Human ANG4 acts as an agonist that binds and activates Tie2, whereas mouse ANG3 is likely to be a Tie2 antagonist, exerting agonist or antagonist activities depending on the cell context. Mouse ANG3 is expressed in various mouse tissues. Mouse angiopoietin 3 is a secreted glycoprotein and member of the angiopoietin family. It has an N-terminal coiled-coil domain and a C-terminal fibrinogen like domain. The coiled coil domains mediate ligand homo-oligomerization and the fibrinogen like domains mediate ligand activity. Recombinant mouse angiopoietin 3 has a calculated molecular mass of 58 kDa. Due to glycosylation, the recombinant protein (containing 3 peptides) has an apparent molecular mass of 85-90 kDa in SDS-PAGE under reducing conditions. Mouse angiopoietin 3 shares 47%, 46%, and 54% sequence identity with mouse ANG1, mouse ANG2, and human ANG4, respectively.
Concentration 0.5 mg/ml
Protein G purified
Buffer System:
Preservative: NoneConstituents: PBS
Protein G purified
Cross-reacts with Mouse. Not yet tested in other species.

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